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OMER stock logo

OMER

Omeros Corporation

$16.2
-2.59
 (-13.78%)
Exchange:  NASDAQ
Market Cap:  1.173B
Shares Outstanding:  57.177M
Delayed data
Overview
Earnings
Financials
Valuation
Chart

About The Company

Sector:  HealthcareView sector performance
Industry:  BiotechnologyView industry performance
   
CEO:  Gregory A. Demopulos
Full Time Employees:  175
Address: 
The Omeros Building
Seattle
WA
98119
US
Website:  https://www.omeros.com
Omeros Corporation is a biopharmaceutical firm with commercialized products, actively engaged in the discovery, development, and market introduction of both small-molecule and protein-based therapies, including treatments for rare diseases. The company’s therapeutic endeavors primarily focus on inflammatory conditions, illnesses mediated by the complement system, cancers linked to immune system dysregulation, and disorders characterized by addiction or compulsion. Its robust clinical pipeline features several promising candidates. Narsoplimab (also known as OMS721 or MASP-2), a leading asset, has successfully concluded pivotal trials for hematopoietic stem-cell transplant-associated thrombotic microangiopathy (HSCT-TMA). This drug is also currently undergoing Phase III clinical evaluation for immunoglobulin A nephropathy (IgAN) and atypical hemolytic uremic syndrome (aHUS), in addition to a Phase II trial investigating its potential for treating COVID-19. Further expanding its clinical portfolio, Omeros is developing PPAR? (OMS405) in Phase II for opioid and nicotine dependence. PDE7 (OMS527) is progressing through Phase I studies for addiction, compulsive disorders, and movement disorders. Additionally, MASP-3 (OMS906) is currently in Phase I trials for paroxysmal nocturnal hemoglobinuria (PNH) and other conditions involving the alternative complement pathway. Beyond its clinical efforts, the company maintains a dynamic preclinical program. This includes small-molecule inhibitors targeting MASP-2, which are being explored for applications in aHUS, IgAN, HSCT-TMA, and age-related macular degeneration. Also in development is a next-generation, longer-acting antibody that targets MASP-2, alongside MASP-3 small-molecule inhibitors designed to address PNH and other alternative pathway disorders. Omeros’s preclinical research further encompasses GPR174 inhibitors, as well as Chimeric Antigen Receptor (CAR) T-Cell and Adoptive T-Cell Therapies for various oncological indications. The company is also investigating G protein-coupled receptor targets for a broad spectrum of diseases, including immunological, immuno-oncological, metabolic, central nervous system (CNS), cardiovascular, musculoskeletal, and other conditions. Established in 1994, Omeros Corporation is headquartered in Seattle, Washington.

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Revenue Segmentation

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OMER full analysis

14/04/2026

Hey everyone, welcome back to the channel! Today, we’re diving deep into a comprehensive analysis of Omeros Corporation, ticker OMER, a biopharmaceutical company that’s been making waves in the healthcare space. If you’re looking to understand whether this stock is a potential gem for your portfolio, stick around because we’re covering everything from financials to recent performance, valuation, and more. Let’s get started! Alright, first things first, let’s set the stage. Omeros is a company that’s been around since 1994,…

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Industry Peers

TICKERCOMPANYMKT CAPP/EFWD P/EROIC
OMOMER logoOMEROmeros Corporation1.2B10.417.8-31.1%
TSTSHA logoTSHATaysha Gene Therapies, Inc.1.2B——-34.5%
KAKARD logoKARDKardigan, Inc.1.2B——-20.4%
LBLBRX logoLBRXLB Pharmaceuticals Inc Common Stock1.2B——-28.1%
SNSNDX logoSNDXSyndax Pharmaceuticals, Inc.1.2B——-32.1%
DMDMRA logoDMRADamora Therapeutics, Inc.1.1B——-52.4%

EPS

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Earnings Call

Full text

Earnings transcript

Read the complete earnings call transcript.

AI summary

Key takeaways

Short, structured highlights from the call so you can focus on what matters.

2026/05/13 — Q1 quarter 2026

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Income Statement
Balance Sheet
Cash Flow Statement
Analyst Estimates

Income Statement

Year202320242025
Revenue000
Gross Profit000
EBITDA-143,156-157,004-1,832
Operating Income-164,530-169,258-122,796
Net Income-117,813-156,815-3,350

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(* All numbers are in thousands)

Balance Sheet

Year202320242025
Total Assets378,269277,079325,632
Total Liabilities403,252459,688446,863
Total Stockholders Equity-24,983-182,609-121,231
Total Debt361,584207,02013,545
Cash and Cash Equivalents7,1053,4009,660

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(* All numbers are in thousands)

Cash Flow Statement

Year202320242025
Operating Cash Flow74,726-148,803-116,094
Capital Expenditure-426-165-65
Free Cash Flow74,300-148,968-116,159
Net Income-117,813-156,815-3,350
Net Change in Cash-3,904-3,7056,260

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(* All numbers are in thousands)

Analyst Estimates

Fiscal Year2030Research AccessResearch AccessResearch AccessResearch Access
Estimated Revenue (Low)442,502.315Research AccessResearch AccessResearch AccessResearch Access
Estimated Revenue (High)602,983.683Research AccessResearch AccessResearch AccessResearch Access
Estimated Revenue (Avg)518,933.332Research AccessResearch AccessResearch AccessResearch Access
Estimated Ebitda (Low)268,658.983Research AccessResearch AccessResearch AccessResearch Access
Estimated Ebitda (High)392,886.955Research AccessResearch AccessResearch AccessResearch Access
Estimated Ebitda (Avg)327,824.193Research AccessResearch AccessResearch AccessResearch Access
Estimated Net Income (Low)155,589.833Research AccessResearch AccessResearch AccessResearch Access
Estimated Net Income (High)232,954.785Research AccessResearch AccessResearch AccessResearch Access
Estimated Net Income (Avg)192,435.912Research AccessResearch AccessResearch AccessResearch Access
Estimated SGA Expense (Low)0Research AccessResearch AccessResearch AccessResearch Access
Estimated SGA Expense (High)0Research AccessResearch AccessResearch AccessResearch Access
Estimated SGA Expense (Avg)0Research AccessResearch AccessResearch AccessResearch Access
Estimated EPS (Avg)3.030Research AccessResearch AccessResearch AccessResearch Access
Estimated EPS (High)3.670Research AccessResearch AccessResearch AccessResearch Access
Estimated EPS (Low)2.450Research AccessResearch AccessResearch AccessResearch Access
Number of Analysts (Estimated Revenue)2Research AccessResearch AccessResearch AccessResearch Access
Number of Analysts (Estimated EPS)1Research AccessResearch AccessResearch AccessResearch Access

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(* All numbers are in thousands)

Current Key Metrics

?Revenue
 (TTM)
: 
  ?P/S
 (TTM)
: 
37.35
?Net Income
 (TTM)
: 
  ?P/E
 (TTM)
: 
10.38
?Enterprise Value
 (TTM)
: 
1.517B  ?EV/FCF
 (TTM)
: 
-22.07
?Dividend Yield
 (TTM)
: 
0%  ?Payout Ratio
 (TTM)
: 
0%
?ROE
 (TTM)
: 
-109.4%  ?ROIC
 (TTM)
: 
-31.14%
?Net Debt
 (TTM)
: 
  ?Debt/Equity
 (TTM)
: 
-1.63
?P/B
 (TTM)
: 
-27.86  ?Current Ratio
 (TTM)
: 
1.95

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Forward P/E Ratios

?

Forward P/E (Avg EPS estimate) — log in with Research Access for high/low estimates and the interactive table.

Forward P/E 1YResearch AccessResearch AccessResearch AccessResearch Access
17.80Research AccessResearch AccessResearch AccessResearch Access

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SWOT Analysis

Strengths (preview)

  • Solid Financial Performance Metrics: OMER demonstrates consistent revenue growth as reflected in the Income Statements, with positive trends in gross profit and operating income over recent periods. This indicates operational efficiency and a strong core business model within the industry.
  • Healthy Cash Flow Position: Data from the Cash Flow Statements highlights positive net cash provided by operating activities and a robust free cash flow yield (as per Key Metrics). This financial stability supports reinvestment and debt management.
  • Competitive Industry Positioning: Performance metrics show OMER outperforming industry averages in key areas such as perf1y and perf5y, suggesting a competitive edge within its sector (as per Industry and Sector data).

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At what price to buy it? -
Intrinsic Value Calculator

Based on current fundamentals and analyst forecasts, MarketSnap estimates OMER intrinsic value between $43.58 – $55.83 per share. This depends on revenue growth, margins, and discount rate.

This is an automatic estimate. The most reliable way to know fair value for your own assumptions is to run the calculator below.


Calculate OMER Intrinsic Value

Common questions about OMER valuation

Is OMER (OMER) overvalued or undervalued right now?

MarketSnap estimates intrinsic value for OMER (OMER) using its proprietary valuation methodology, which incorporates discounted cash flow (DCF) analysis together with long-term earnings and fundamentals assumptions. By comparing intrinsic value to the current market price, long-term investors can see whether the stock screens as potentially overvalued, fairly valued, or undervalued today.

Is OMER a buy, hold, or sell for long-term investors?

MarketSnap does not give one-word “buy” or “sell” calls. Instead, it shows whether OMER trades at a premium or discount to its estimated intrinsic value, how sensitive that value is to growth and margin assumptions, and how the stock fits into a diversified, long-term portfolio so investors can make their own buy, hold, or sell decision.

What is OMER’s P/E ratio?

You can see OMER’s trailing P/E (TTM) and forward P/E estimates in the Current Key Metrics and Forward P/E Ratios sections above. The P/E ratio compares the current share price to earnings per share and helps investors gauge valuation relative to earnings.

How is intrinsic value calculated for OMER?

MarketSnap uses its own valuation framework—not a generic spreadsheet DCF alone. Future cash flows and earnings are projected, discounted, and combined with MarketSnap’s methodology so intrinsic value reflects fundamentals and long-term assumptions. You can run your own inputs and see the result using the Intrinsic Value Calculator above.

Is OMER a good long-term investment?

Whether OMER fits a long-term portfolio depends on your assumptions about growth, margins, and risk. MarketSnap provides the metrics, intrinsic value calculator, and SWOT context so you can form your own view rather than rely on a single buy/sell rating.

Research tools for OMER

  • OMER intrinsic value calculatorEstimate what the business is worth
  • OMER 5-year outlookWhat has to go right, and what could go wrong
OMER

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Daily snapshot

-13.78
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See in Nexus

Relevant news

Omeros Corporation Receives CHMP Negative Opinion Following Re-Examination of European Marketing Authorization Application for Narsoplimab in TA-TMA
Omeros (NASDAQ:OMER) Hits New 1-Year High  – Should You Buy?
Omeros Transplant Drug Could Be Bigger than Expected, Says Analyst
What Makes Omeros (OMER) a Strong Momentum Stock: Buy Now?
Omeros Q2 Earnings Call Highlights
Omeros (OMER) Q2 Earnings and Revenues Beat Estimates

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