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VRTX stock logo

VRTX

Vertex Pharmaceuticals Incorporated

$438.71
-8.55
 (-1.91%)
Exchange:  NASDAQ
Market Cap:  111.432B
Shares Outstanding:  13.03M
Overview
Earnings
Financials
Valuation
Chart

About The Company

Sector:  Healthcare
Industry:  Biotechnology
   
CEO:  Reshma Kewalramani
Full Time Employees:  6100
Address: 
50 Northern Avenue
Boston
MA
2210
US
Website:  https://www.vrtx.com
Vertex Pharmaceuticals Incorporated, a biotechnology company, engages in developing and commercializing therapies for treating cystic fibrosis. The company markets SYMDEKO/SYMKEVI, ORKAMBI, and KALYDECO to treat patients with cystic fibrosis who have specific mutations in their cystic fibrosis transmembrane conductance regulator gene; and TRIKAFTA for the treatment of patients with CF 6 years of age or older who have at least one F508del mutation. Its pipeline includes VX-864 for the treatment of AAT deficiency, which is in Phase 2 clinical trial; VX-147 for the treatment of APOL1-mediated focal segmental glomerulosclerosis, or FSGS, and other serious kidney diseases which is in Phase 2 clinical trial; VX- 880, treatment for Type 1 Diabetes which is in Phase 1/2 clinical trial; VX-548, a NaV1.8 inhibitor for treatments of acute, neuropathic, musculoskeletal pain which is in Phase 2 clinical trial; and CTX001 for the treatment severe SCD and TDT which is in Phase 3 clinical trial. The company sells its products primarily to specialty pharmacy and specialty distributors in the United States, as well as specialty distributors and retail chains, and hospitals and clinics internationally. It has collaborations with Affinia Therapeutics, Inc.; Arbor Biotechnologies, Inc.; CRISPR Therapeutics AG.; Kymera Therapeutics, Inc.; Mammoth Biosciences, Inc.; Moderna, Inc.; Obsidian Therapeutics, Inc.; and Skyhawk Therapeutics, Inc.; as well as Ribometrix, Inc.; Genomics plc; Merck KGaA; Darmstadt, Germany, and X-Chem, Inc. Vertex Pharmaceuticals Incorporated was founded in 1989 and is headquartered in Boston, Massachusetts.

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Revenue Segmentation

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EPS

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Earnings Call

Full text

Earnings transcript

Read the complete earnings call transcript.

AI summary

Key takeaways

Short, structured highlights from the call so you can focus on what matters.

2025/05/05 — Q1 quarter 2025

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Income Statement
Balance Sheet
Cash Flow Statement
Analyst Estimates

Income Statement

Year202320242025
Revenue9,869,20011,020,10012,074,600
Gross Profit8,607,0009,489,60010,267,500
EBITDA4,605,200486,3004,967,900
Operating Income3,832,000-232,9004,760,700
Net Income3,619,600-535,6003,953,200

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(* All numbers are in thousands)

Balance Sheet

Year202320242025
Total Assets22,730,20022,533,20025,643,000
Total Liabilities5,149,8006,123,6006,977,200
Total Stockholders Equity17,580,40016,409,60018,665,800
Total Debt808,4001,749,5003,693,000
Cash and Cash Equivalents10,369,1004,569,6005,084,800

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(* All numbers are in thousands)

Cash Flow Statement

Year202320242025
Operating Cash Flow3,537,300-492,6003,631,400
Capital Expenditure-258,399.999-297,700-437,600
Free Cash Flow3,278,900.001-790,3003,193,800
Net Income3,619,600-535,6003,953,200
Net Change in Cash-139,700-5,800,100515,600

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(* All numbers are in thousands)

Analyst Estimates

Fiscal Year2030Full AccessFull AccessFull AccessFull Access
Estimated Revenue (Low)18,642,759.987Full AccessFull AccessFull AccessFull Access
Estimated Revenue (High)21,437,041.236Full AccessFull AccessFull AccessFull Access
Estimated Revenue (Avg)19,779,347.733Full AccessFull AccessFull AccessFull Access
Estimated Ebitda (Low)6,726,391.437Full AccessFull AccessFull AccessFull Access
Estimated Ebitda (High)7,734,580.647Full AccessFull AccessFull AccessFull Access
Estimated Ebitda (Avg)7,136,477.395Full AccessFull AccessFull AccessFull Access
Estimated Net Income (Low)7,963,428.030Full AccessFull AccessFull AccessFull Access
Estimated Net Income (High)9,544,023.756Full AccessFull AccessFull AccessFull Access
Estimated Net Income (Avg)8,606,343.393Full AccessFull AccessFull AccessFull Access
Estimated SGA Expense (Low)2,274,137.414Full AccessFull AccessFull AccessFull Access
Estimated SGA Expense (High)2,614,997.862Full AccessFull AccessFull AccessFull Access
Estimated SGA Expense (Avg)2,412,784.090Full AccessFull AccessFull AccessFull Access
Estimated EPS (Avg)33.360Full AccessFull AccessFull AccessFull Access
Estimated EPS (High)36.990Full AccessFull AccessFull AccessFull Access
Estimated EPS (Low)30.870Full AccessFull AccessFull AccessFull Access
Number of Analysts (Estimated Revenue)11Full AccessFull AccessFull AccessFull Access
Number of Analysts (Estimated EPS)5Full AccessFull AccessFull AccessFull Access

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(* All numbers are in thousands)

Current Key Metrics

?Revenue
 (TTM)
: 
10.984B  ?P/S
 (TTM)
: 
9.32
?Net Income
 (TTM)
: 
-535600000  ?P/E
 (TTM)
: 
28.34
?Enterprise Value
 (TTM)
: 
111.018B  ?EV/FCF
 (TTM)
: 
34.76
?Dividend Yield
 (TTM)
: 
0  ?Payout Ratio
 (TTM)
: 
0
?ROE
 (TTM)
: 
0.23  ?ROIC
 (TTM)
: 
0.16
?Net Debt
 (TTM)
: 
-4369000000  ?Debt/Equity
 (TTM)
: 
0.21
?P/B
 (TTM)
: 
6  ?Current Ratio
 (TTM)
: 
2.9

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Forward P/E Ratios

?

Forward P/E (Avg EPS estimate) — log in with Full Access for high/low estimates and the interactive table.

Forward P/E 1YFull AccessFull AccessFull AccessFull Access
22.89Full AccessFull AccessFull AccessFull Access

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SWOT Analysis

Strengths (preview)
  • Robust Financial Performance: Vertex Pharmaceuticals reported strong financial results in Q4 2024, with revenue and net income growth exceeding expectations, as highlighted in the earnings call transcript. Key metrics such as operating cash flow and free cash flow demonstrate solid liquidity and operational efficiency, supporting sustained growth.
  • Innovative Product Pipeline: The company emphasized advancements in its clinical pipeline during the Q4 2024 earnings call, with new product launches contributing to revenue growth. This focus on innovation aligns with industry trends in biotechnology, positioning VRTX as a leader in its sector.
  • Strong Profitability Metrics: High gross profit margin and net profit margin (TTM) reflect efficient cost management and profitability compared to industry averages, providing a competitive edge within the biotechnology sector.

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At what price to buy it? -
Intrinsic Value Calculator

This is an automatic estimate. The most reliable way to know fair value for your own assumptions is to run the calculator below.


Calculate VRTX Intrinsic Value

Common questions about VRTX valuation

Is Vertex Pharmaceuticals Incorporated (VRTX) overvalued or undervalued right now?

MARKETSnap estimates intrinsic value for Vertex Pharmaceuticals Incorporated (VRTX) using its proprietary valuation methodology, which incorporates discounted cash flow (DCF) analysis together with long-term earnings and fundamentals assumptions. By comparing intrinsic value to the current market price, long-term investors can see whether the stock screens as potentially overvalued, fairly valued, or undervalued today.

Is VRTX a buy, hold, or sell for long-term investors?

MARKETSnap does not give one-word “buy” or “sell” calls. Instead, it shows whether VRTX trades at a premium or discount to its estimated intrinsic value, how sensitive that value is to growth and margin assumptions, and how the stock fits into a diversified, long-term portfolio so investors can make their own buy, hold, or sell decision.

What is VRTX’s P/E ratio?

You can see VRTX’s trailing P/E (TTM) and forward P/E estimates in the Current Key Metrics and Forward P/E Ratios sections above. The P/E ratio compares the current share price to earnings per share and helps investors gauge valuation relative to earnings.

How is intrinsic value calculated for VRTX?

MARKETSnap uses its own valuation framework—not a generic spreadsheet DCF alone. Future cash flows and earnings are projected, discounted, and combined with MARKETSnap’s methodology so intrinsic value reflects fundamentals and long-term assumptions. You can run your own inputs and see the result using the Intrinsic Value Calculator above.

Is VRTX a good long-term investment?

Whether VRTX fits a long-term portfolio depends on your assumptions about growth, margins, and risk. MARKETSnap provides the metrics, intrinsic value calculator, and SWOT context so you can form your own view rather than rely on a single buy/sell rating.

VRTX

1-day price chart preview. Log in for 1W through 5Y ranges and period tabs.

Daily snapshot

-1.91
MARKETSnap

Trading Metrics:

Open: 444.54   Previous Close: 447.26
Day Low: 436.56   Day High: 449.62
Year Low: 362.5   Year High: 510.77
Price Avg 50: 467.89   Price Avg 200: 438.32
Volume: 1.243M   Average Volume: 1.382M

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VRTX full analysis

24/02/2026

Hey everyone, welcome back to the channel! Today, we’re diving deep into a comprehensive analysis of Vertex Pharmaceuticals, ticker VRTX, a powerhouse in the biotech space. If you’re looking to invest in a company that’s been making waves with its innovative therapies, stick around because we’re breaking down everything from financials to future potential. Let’s get started! So, why are we talking about Vertex Pharmaceuticals? Well, this isn’t just any biotech company—it’s a leader in developing treatments for serious diseases,…

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See in Nexus

Relevant news

Vertex Pharmaceuticals (VRTX) Stock Sinks As Market Gains: Here's Why
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Vertex Pharmaceuticals (VRTX) Stock Sinks As Market Gains: Here's Why
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Aberdeen Group plc Has $118.81 Million Stock Holdings in Vertex Pharmaceuticals Incorporated $VRTX
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