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TSHA stock logo

TSHA

Taysha Gene Therapies, Inc.

$6.09
0.07
 (1.08%)
Exchange:  NASDAQ
Market Cap:  1.946B
Shares Outstanding:  36.992M
Delayed data
Calculate TSHA Intrinsic Value
5-year outlook →
Overview
Earnings
Financials
Valuation
Chart

About The Company

Sector:  Healthcare
Industry:  Biotechnology
   
CEO:  Sean Nolan
Full Time Employees:  99
Address: 
3000 Pegasus Park Drive
Dallas
TX
75247
US
Website:  https://www.tayshagtx.com
Taysha Gene Therapies, Inc. is a biotech firm specializing in the creation and market introduction of gene therapies that utilize adeno-associated virus (AAV) vectors. Its core mission is to tackle inherited diseases affecting the central nervous system (CNS). The company’s development pipeline features several key programs: TSHA-120 is aimed at giant axonal neuropathy; TSHA-102 is in development for Rett syndrome; TSHA-121 and TSHA-118 are both being advanced for CLN1 disease; TSHA-105 addresses SLC13A5 Deficiency; and TSHA-101 targets GM2 gangliosidosis. Furthermore, Taysha has forged a strategic alliance with The University of Texas Southwestern Medical Center to jointly advance and bring to market innovative gene therapy solutions. Founded in 2019, the company operates from its headquarters in Dallas, Texas.

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Revenue Segmentation

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EPS

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Earnings Call

Full text

Earnings transcript

Read the complete earnings call transcript.

AI summary

Key takeaways

Short, structured highlights from the call so you can focus on what matters.

2026/05/06 — Q1 quarter 2026

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Income Statement
Balance Sheet
Cash Flow Statement
Analyst Estimates

Income Statement

Year202320242025
Revenue15,4518,3339,773
Gross Profit15,4518,3339,773
EBITDA-105,197-87,951-107,787
Operating Income-72,439-91,459-110,498
Net Income-111,566-89,298-108,995

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(* All numbers are in thousands)

Balance Sheet

Year202320242025
Total Assets172,731160,364343,320
Total Liabilities97,79488,83996,382
Total Stockholders Equity74,93771,525246,938
Total Debt61,10763,18018,172
Cash and Cash Equivalents143,940139,036319,767

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(* All numbers are in thousands)

Cash Flow Statement

Year202320242025
Operating Cash Flow-73,018-81,225-93,090
Capital Expenditure-7,369-374-738
Free Cash Flow-80,387-81,599-93,828
Net Income-111,566-89,298-108,995
Net Change in Cash56,509-4,904180,895

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(* All numbers are in thousands)

Analyst Estimates

Fiscal Year2030Research AccessResearch AccessResearch AccessResearch Access
Estimated Revenue (Low)735,693.352Research AccessResearch AccessResearch AccessResearch Access
Estimated Revenue (High)1,455,501.559Research AccessResearch AccessResearch AccessResearch Access
Estimated Revenue (Avg)957,466.800Research AccessResearch AccessResearch AccessResearch Access
Estimated Ebitda (Low)-873,300.935Research AccessResearch AccessResearch AccessResearch Access
Estimated Ebitda (High)-441,416.011Research AccessResearch AccessResearch AccessResearch Access
Estimated Ebitda (Avg)-574,480.080Research AccessResearch AccessResearch AccessResearch Access
Estimated Net Income (Low)217,634.334Research AccessResearch AccessResearch AccessResearch Access
Estimated Net Income (High)521,971.358Research AccessResearch AccessResearch AccessResearch Access
Estimated Net Income (Avg)311,399.461Research AccessResearch AccessResearch AccessResearch Access
Estimated SGA Expense (Low)3,505,237.224Research AccessResearch AccessResearch AccessResearch Access
Estimated SGA Expense (High)6,934,789.109Research AccessResearch AccessResearch AccessResearch Access
Estimated SGA Expense (Avg)4,561,884.730Research AccessResearch AccessResearch AccessResearch Access
Estimated EPS (Avg)0.970Research AccessResearch AccessResearch AccessResearch Access
Estimated EPS (High)1.630Research AccessResearch AccessResearch AccessResearch Access
Estimated EPS (Low)0.680Research AccessResearch AccessResearch AccessResearch Access
Number of Analysts (Estimated Revenue)3Research AccessResearch AccessResearch AccessResearch Access
Number of Analysts (Estimated EPS)1Research AccessResearch AccessResearch AccessResearch Access

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(* All numbers are in thousands)

Current Key Metrics

?Revenue
 (TTM)
: 
8.333M  ?P/S
 (TTM)
: 
355.14
?Net Income
 (TTM)
: 
-89298000  ?P/E
 (TTM)
: 
-14.41
?Enterprise Value
 (TTM)
: 
1.548B  ?EV/FCF
 (TTM)
: 
-11.42
?Dividend Yield
 (TTM)
: 
0%  ?Payout Ratio
 (TTM)
: 
0%
?ROE
 (TTM)
: 
-56.19%  ?ROIC
 (TTM)
: 
-34.46%
?Net Debt
 (TTM)
: 
-75535000  ?Debt/Equity
 (TTM)
: 
0.14
?P/B
 (TTM)
: 
5.8  ?Current Ratio
 (TTM)
: 
17.76

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Forward P/E Ratios

?

Forward P/E (Avg EPS estimate) — log in with Research Access for high/low estimates and the interactive table.

Forward P/E 1YResearch AccessResearch AccessResearch AccessResearch Access
N/AResearch AccessResearch AccessResearch AccessResearch Access

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SWOT Analysis

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At what price to buy it? -
Intrinsic Value Calculator

This is an automatic estimate. The most reliable way to know fair value for your own assumptions is to run the calculator below.

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Common questions about TSHA valuation

Is Taysha Gene Therapies, Inc. (TSHA) overvalued or undervalued right now?

MARKETSnap estimates intrinsic value for Taysha Gene Therapies, Inc. (TSHA) using its proprietary valuation methodology, which incorporates discounted cash flow (DCF) analysis together with long-term earnings and fundamentals assumptions. By comparing intrinsic value to the current market price, long-term investors can see whether the stock screens as potentially overvalued, fairly valued, or undervalued today.

Is TSHA a buy, hold, or sell for long-term investors?

MARKETSnap does not give one-word “buy” or “sell” calls. Instead, it shows whether TSHA trades at a premium or discount to its estimated intrinsic value, how sensitive that value is to growth and margin assumptions, and how the stock fits into a diversified, long-term portfolio so investors can make their own buy, hold, or sell decision.

What is TSHA’s P/E ratio?

You can see TSHA’s trailing P/E (TTM) and forward P/E estimates in the Current Key Metrics and Forward P/E Ratios sections above. The P/E ratio compares the current share price to earnings per share and helps investors gauge valuation relative to earnings.

How is intrinsic value calculated for TSHA?

MARKETSnap uses its own valuation framework—not a generic spreadsheet DCF alone. Future cash flows and earnings are projected, discounted, and combined with MARKETSnap’s methodology so intrinsic value reflects fundamentals and long-term assumptions. You can run your own inputs and see the result using the Intrinsic Value Calculator above.

Is TSHA a good long-term investment?

Whether TSHA fits a long-term portfolio depends on your assumptions about growth, margins, and risk. MARKETSnap provides the metrics, intrinsic value calculator, and SWOT context so you can form your own view rather than rely on a single buy/sell rating.

TSHA

1-day price chart preview. Log in for 1W through 5Y ranges and period tabs.

Daily snapshot

1.08
MARKETSnap

Trading Metrics:

Open: 5.99   Previous Close: 6.02
Day Low: 5.89   Day High: 6.09
Year Low: 2.71   Year High: 7.3
Price Avg 50: 6.16   Price Avg 200: 5.38
Volume: 476270   Average Volume: 3.064M

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Relevant news

Taysha Gene Therapies, Inc. (TSHA) Q2 2026 Earnings Call Transcript
11-08-2026 21:37
Taysha Gene Therapies, Inc. (TSHA) Q2 2026 Earnings Call Transcript
Taysha Gene Therapies Q2 Earnings Call Highlights
11-08-2026 21:04
Taysha Gene Therapies Q2 Earnings Call Highlights
Taysha: 'Buy' On Interim Analysis Of TSHA-102 First Half 2027 And Broad Label Potential
30-06-2026 09:38
Taysha: 'Buy' On Interim Analysis Of TSHA-102 First Half 2027 And Broad Label Potential
Taysha Gene Therapies Announces Multiple Presentations Highlighting its TSHA-102 Clinical Program at the 2026 IRSF Rett Syndrome Scientific Meeting
25-06-2026 16:01
Taysha Gene Therapies Announces Multiple Presentations Highlighting its TSHA-102 Clinical Program at the 2026 IRSF Rett Syndrome Scientific Meeting
Taysha Gene Therapies Announces Pricing of Public Offering of Common Stock and Pre-Funded Warrants
24-06-2026 22:33
Taysha Gene Therapies Announces Pricing of Public Offering of Common Stock and Pre-Funded Warrants
Taysha Gene Therapies, Inc. (TSHA) Discusses Longer-Term Clinical Data and Program Update for TSHA-102 in Rett Syndrome Transcript
22-06-2026 16:42
Taysha Gene Therapies, Inc. (TSHA) Discusses Longer-Term Clinical Data and Program Update for TSHA-102 in Rett Syndrome Transcript

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