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STOK stock logo

STOK

Stoke Therapeutics, Inc.

$32.74
0.75
 (2.34%)
[ms_data_label text=’Delayed data’]
Exchange:  NASDAQ
Market Cap:  1.937B
Shares Outstanding:  12.785M
Overview
Earnings
Financials
Valuation
Chart

About The Company

Sector:  Healthcare
Industry:  Biotechnology
   
CEO:  Ian F. Smith
Full Time Employees:  128
Address: 
45 Wiggins Avenue
Bedford
MA
1730
US
Website:  https://www.stoketherapeutics.com
Stoke Therapeutics, Inc., an early-stage biopharmaceutical company, develops novel antisense oligonucleotide (ASO) medicines to treat the underlying causes of severe genetic diseases in the United States. The company utilizes its proprietary Targeted Augmentation of Nuclear Gene Output to design ASOs to precisely upregulate protein expression. Its lead clinical candidate is STK-001, which is in phase I/IIa clinical trial to treat Dravet syndrome, a severe and progressive genetic epilepsy; and STK-002, which is in preclinical stage for the treatment of autosomal dominant optic atrophy. It had entered into a license and collaboration agreement with Acadia Pharmaceuticals Inc. for the discovery, development, and commercialization of novel RNA-based medicines for the treatment of severe and rare genetic neurodevelopmental diseases of the central nervous system. The company was formerly known as ASOthera Pharmaceuticals, Inc. and changed its name to Stoke Therapeutics, Inc. in May 2016. Stoke Therapeutics, Inc. was incorporated in 2014 and is headquartered in Bedford, Massachusetts.

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Revenue Segmentation

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EPS

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Earnings Call

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Income Statement
Balance Sheet
Cash Flow Statement
Analyst Estimates

Income Statement

Year202320242025
Revenue8,78036,555184,420
Gross Profit8,78036,555184,420
EBITDA-112,304-99,195-18,820
Operating Income-114,773-101,372-20,590
Net Income-104,699-88,981-6,885

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(* All numbers are in thousands)

Balance Sheet

Year202320242025
Total Assets228,342271,555418,434
Total Liabilities68,77742,5348,102
Total Stockholders Equity159,565229,021352,457
Total Debt2,0622,3220
Cash and Cash Equivalents191,442127,98384,220

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(* All numbers are in thousands)

Cash Flow Statement

Year202320242025
Operating Cash Flow-81,067-86,85145,585
Capital Expenditure-1,616-203-670
Free Cash Flow-82,683-87,05444,915
Net Income-104,699-88,981-6,885
Net Change in Cash77,886-63,232-43,838

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(* All numbers are in thousands)

Analyst Estimates

Fiscal Year2030Full AccessFull AccessFull AccessFull Access
Estimated Revenue (Low)263,041.891Full AccessFull AccessFull AccessFull Access
Estimated Revenue (High)881,349.342Full AccessFull AccessFull AccessFull Access
Estimated Revenue (Avg)547,208Full AccessFull AccessFull AccessFull Access
Estimated Ebitda (Low)-370,528.018Full AccessFull AccessFull AccessFull Access
Estimated Ebitda (High)-110,585.423Full AccessFull AccessFull AccessFull Access
Estimated Ebitda (Avg)-230,051.679Full AccessFull AccessFull AccessFull Access
Estimated Net Income (Low)33,911.866Full AccessFull AccessFull AccessFull Access
Estimated Net Income (High)187,227.375Full AccessFull AccessFull AccessFull Access
Estimated Net Income (Avg)104,373.813Full AccessFull AccessFull AccessFull Access
Estimated SGA Expense (Low)554,636.140Full AccessFull AccessFull AccessFull Access
Estimated SGA Expense (High)1,858,366.344Full AccessFull AccessFull AccessFull Access
Estimated SGA Expense (Avg)1,153,813.683Full AccessFull AccessFull AccessFull Access
Estimated EPS (Avg)1.760Full AccessFull AccessFull AccessFull Access
Estimated EPS (High)3.160Full AccessFull AccessFull AccessFull Access
Estimated EPS (Low)0.570Full AccessFull AccessFull AccessFull Access
Number of Analysts (Estimated Revenue)4Full AccessFull AccessFull AccessFull Access
Number of Analysts (Estimated EPS)6Full AccessFull AccessFull AccessFull Access

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(* All numbers are in thousands)

Current Key Metrics

?Revenue
 (TTM)
: 
8.78M  ?P/S
 (TTM)
: 
11.95
?Net Income
 (TTM)
: 
-104699000  ?P/E
 (TTM)
: 
-316.07
?Enterprise Value
 (TTM)
: 
2.12B  ?EV/FCF
 (TTM)
: 
47.21
?Dividend Yield
 (TTM)
: 
0  ?Payout Ratio
 (TTM)
: 
0
?ROE
 (TTM)
: 
-0.02  ?ROIC
 (TTM)
: 
-0.06
?Net Debt
 (TTM)
: 
-233969000  ?Debt/Equity
 (TTM)
: 
0
?P/B
 (TTM)
: 
6.17  ?Current Ratio
 (TTM)
: 
5.28

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Forward P/E Ratios

?

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Forward P/E 1YFull AccessFull AccessFull AccessFull Access
N/AFull AccessFull AccessFull AccessFull Access

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SWOT Analysis

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At what price to buy it? -
Intrinsic Value Calculator

This is an automatic estimate. The most reliable way to know fair value for your own assumptions is to run the calculator below.


Calculate STOK Intrinsic Value

Common questions about STOK valuation

Is Stoke Therapeutics, Inc. (STOK) overvalued or undervalued right now?

MARKETSnap estimates intrinsic value for Stoke Therapeutics, Inc. (STOK) using its proprietary valuation methodology, which incorporates discounted cash flow (DCF) analysis together with long-term earnings and fundamentals assumptions. By comparing intrinsic value to the current market price, long-term investors can see whether the stock screens as potentially overvalued, fairly valued, or undervalued today.

Is STOK a buy, hold, or sell for long-term investors?

MARKETSnap does not give one-word “buy” or “sell” calls. Instead, it shows whether STOK trades at a premium or discount to its estimated intrinsic value, how sensitive that value is to growth and margin assumptions, and how the stock fits into a diversified, long-term portfolio so investors can make their own buy, hold, or sell decision.

What is STOK’s P/E ratio?

You can see STOK’s trailing P/E (TTM) and forward P/E estimates in the Current Key Metrics and Forward P/E Ratios sections above. The P/E ratio compares the current share price to earnings per share and helps investors gauge valuation relative to earnings.

How is intrinsic value calculated for STOK?

MARKETSnap uses its own valuation framework—not a generic spreadsheet DCF alone. Future cash flows and earnings are projected, discounted, and combined with MARKETSnap’s methodology so intrinsic value reflects fundamentals and long-term assumptions. You can run your own inputs and see the result using the Intrinsic Value Calculator above.

Is STOK a good long-term investment?

Whether STOK fits a long-term portfolio depends on your assumptions about growth, margins, and risk. MARKETSnap provides the metrics, intrinsic value calculator, and SWOT context so you can form your own view rather than rely on a single buy/sell rating.

STOK

1-day price chart preview. Log in for 1W through 5Y ranges and period tabs.

[ms_data_label text="Daily snapshot"]

2.34
MARKETSnap

Trading Metrics:

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Open: [ms_cell_or_dash table='trading_quote' column='open']   Previous Close: [ms_cell_or_dash table='trading_quote' column='previousClose']
Day Low: [ms_cell_or_dash table='trading_quote' column='dayLow']   Day High: [ms_cell_or_dash table='trading_quote' column='dayHigh']
Year Low: 5.35   Year High: 40.22
Price Avg 50: 33.15   Price Avg 200: 25.95
Volume: 563638   Average Volume: 740040

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See in Nexus

Relevant news

Stoke Therapeutics: Zorevunersen Has Disease-Modifying Potential In Dravet Syndrome
01-05-2026 16:39
Stoke Therapeutics: Zorevunersen Has Disease-Modifying Potential In Dravet Syndrome
Stoke Therapeutics Appoints Clare Kahn, Ph.D., to its Board of Directors
07-04-2026 16:01
Stoke Therapeutics Appoints Clare Kahn, Ph.D., to its Board of Directors
Stoke Therapeutics Stock Up 340% as Chair Sells $174K in Shares
27-03-2026 20:32
Stoke Therapeutics Stock Up 340% as Chair Sells $174K in Shares
Assenagon Asset Management S.A. Boosts Position in Stoke Therapeutics, Inc. $STOK
26-03-2026 03:07
Assenagon Asset Management S.A. Boosts Position in Stoke Therapeutics, Inc. $STOK
Stoke Therapeutics CMO Sells $457,000 in Stock Amid 300% Rally
24-03-2026 12:35
Stoke Therapeutics CMO Sells $457,000 in Stock Amid 300% Rally
The New England Journal of Medicine Publishes First Data to Demonstrate the Potential for Disease Modification in Dravet Syndrome
04-03-2026 17:06
The New England Journal of Medicine Publishes First Data to Demonstrate the Potential for Disease Modification in Dravet Syndrome

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