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STOK stock logo

STOK

Stoke Therapeutics, Inc.

$32.75
-0.34
 (-1.03%)
Exchange:  NASDAQ
Market Cap:  2.113B
Shares Outstanding:  12.785M
Delayed data
Calculate STOK Intrinsic Value
5-year outlook →
Overview
Earnings
Financials
Valuation
Chart

About The Company

Sector:  Healthcare
Industry:  Biotechnology
   
CEO:  Ian F. Smith
Full Time Employees:  170
Address: 
45 Wiggins Avenue
Bedford
MA
1730
US
Website:  https://www.stoketherapeutics.com
Stoke Therapeutics, Inc. is an emerging biopharmaceutical company dedicated to developing innovative antisense oligonucleotide (ASO) therapies. Its primary focus is to target and address the fundamental causes of severe genetic disorders, particularly within the United States. The company employs its exclusive Targeted Augmentation of Nuclear Gene Output (TANGO) platform to engineer ASOs that precisely enhance protein expression. Stoke’s most advanced candidate, STK-001, is currently progressing through Phase I/IIa clinical trials for Dravet syndrome, a severe and debilitating genetic epilepsy. Additionally, STK-002 is in the preclinical development stage for treating autosomal dominant optic atrophy. The company has also established a licensing and collaborative agreement with Acadia Pharmaceuticals Inc. to identify, develop, and market new RNA-based medicines for critical and rare genetic neurodevelopmental conditions impacting the central nervous system. Formerly known as ASOthera Pharmaceuticals, Inc., the company rebranded to Stoke Therapeutics, Inc. in May 2016. Founded in 2014, Stoke Therapeutics, Inc. maintains its headquarters in Bedford, Massachusetts.

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Revenue Segmentation

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EPS

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Earnings Call

Full text

Earnings transcript

Read the complete earnings call transcript.

AI summary

Key takeaways

Short, structured highlights from the call so you can focus on what matters.

2026/08/03 — Q2 quarter 2026

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Income Statement
Balance Sheet
Cash Flow Statement
Analyst Estimates

Income Statement

Year202320242025
Revenue8,78036,555184,420
Gross Profit8,78036,555184,420
EBITDA-102,230-86,804-5,115
Operating Income-114,773-101,372-20,590
Net Income-104,699-88,981-6,885

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(* All numbers are in thousands)

Balance Sheet

Year202320242025
Total Assets228,342271,555418,434
Total Liabilities68,77742,5348,102
Total Stockholders Equity159,565229,021352,457
Total Debt2,0622,3220
Cash and Cash Equivalents191,442127,98384,220

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(* All numbers are in thousands)

Cash Flow Statement

Year202320242025
Operating Cash Flow-81,067-86,85145,585
Capital Expenditure-1,616-203-670
Free Cash Flow-82,683-87,05444,915
Net Income-104,699-88,981-6,885
Net Change in Cash77,886-63,232-43,838

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(* All numbers are in thousands)

Analyst Estimates

Fiscal Year2030Research AccessResearch AccessResearch AccessResearch Access
Estimated Revenue (Low)178,337.708Research AccessResearch AccessResearch AccessResearch Access
Estimated Revenue (High)1,162,470.424Research AccessResearch AccessResearch AccessResearch Access
Estimated Revenue (Avg)623,996.500Research AccessResearch AccessResearch AccessResearch Access
Estimated Ebitda (Low)-471,436.533Research AccessResearch AccessResearch AccessResearch Access
Estimated Ebitda (High)-72,324.343Research AccessResearch AccessResearch AccessResearch Access
Estimated Ebitda (Avg)-253,059.983Research AccessResearch AccessResearch AccessResearch Access
Estimated Net Income (Low)9,097.843Research AccessResearch AccessResearch AccessResearch Access
Estimated Net Income (High)269,839.322Research AccessResearch AccessResearch AccessResearch Access
Estimated Net Income (Avg)127,173.199Research AccessResearch AccessResearch AccessResearch Access
Estimated SGA Expense (Low)376,033.405Research AccessResearch AccessResearch AccessResearch Access
Estimated SGA Expense (High)2,451,123.304Research AccessResearch AccessResearch AccessResearch Access
Estimated SGA Expense (Avg)1,315,725.829Research AccessResearch AccessResearch AccessResearch Access
Estimated EPS (Avg)2.150Research AccessResearch AccessResearch AccessResearch Access
Estimated EPS (High)4.560Research AccessResearch AccessResearch AccessResearch Access
Estimated EPS (Low)0.150Research AccessResearch AccessResearch AccessResearch Access
Number of Analysts (Estimated Revenue)5Research AccessResearch AccessResearch AccessResearch Access
Number of Analysts (Estimated EPS)4Research AccessResearch AccessResearch AccessResearch Access

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(* All numbers are in thousands)

Current Key Metrics

?Revenue
 (TTM)
: 
8.78M  ?P/S
 (TTM)
: 
75.52
?Net Income
 (TTM)
: 
-104699000  ?P/E
 (TTM)
: 
-9.61
?Enterprise Value
 (TTM)
: 
1.976B  ?EV/FCF
 (TTM)
: 
-10.94
?Dividend Yield
 (TTM)
: 
0%  ?Payout Ratio
 (TTM)
: 
0%
?ROE
 (TTM)
: 
-59.36%  ?ROIC
 (TTM)
: 
-62.74%
?Net Debt
 (TTM)
: 
-233969000  ?Debt/Equity
 (TTM)
: 
0.01
?P/B
 (TTM)
: 
6.17  ?Current Ratio
 (TTM)
: 
7.69

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Forward P/E Ratios

?

Forward P/E (Avg EPS estimate) — log in with Research Access for high/low estimates and the interactive table.

Forward P/E 1YResearch AccessResearch AccessResearch AccessResearch Access
N/AResearch AccessResearch AccessResearch AccessResearch Access

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SWOT Analysis

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At what price to buy it? -
Intrinsic Value Calculator

This is an automatic estimate. The most reliable way to know fair value for your own assumptions is to run the calculator below.

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Common questions about STOK valuation

Is Stoke Therapeutics, Inc. (STOK) overvalued or undervalued right now?

MARKETSnap estimates intrinsic value for Stoke Therapeutics, Inc. (STOK) using its proprietary valuation methodology, which incorporates discounted cash flow (DCF) analysis together with long-term earnings and fundamentals assumptions. By comparing intrinsic value to the current market price, long-term investors can see whether the stock screens as potentially overvalued, fairly valued, or undervalued today.

Is STOK a buy, hold, or sell for long-term investors?

MARKETSnap does not give one-word “buy” or “sell” calls. Instead, it shows whether STOK trades at a premium or discount to its estimated intrinsic value, how sensitive that value is to growth and margin assumptions, and how the stock fits into a diversified, long-term portfolio so investors can make their own buy, hold, or sell decision.

What is STOK’s P/E ratio?

You can see STOK’s trailing P/E (TTM) and forward P/E estimates in the Current Key Metrics and Forward P/E Ratios sections above. The P/E ratio compares the current share price to earnings per share and helps investors gauge valuation relative to earnings.

How is intrinsic value calculated for STOK?

MARKETSnap uses its own valuation framework—not a generic spreadsheet DCF alone. Future cash flows and earnings are projected, discounted, and combined with MARKETSnap’s methodology so intrinsic value reflects fundamentals and long-term assumptions. You can run your own inputs and see the result using the Intrinsic Value Calculator above.

Is STOK a good long-term investment?

Whether STOK fits a long-term portfolio depends on your assumptions about growth, margins, and risk. MARKETSnap provides the metrics, intrinsic value calculator, and SWOT context so you can form your own view rather than rely on a single buy/sell rating.

STOK

1-day price chart preview. Log in for 1W through 5Y ranges and period tabs.

Daily snapshot

-1.03
MARKETSnap

Trading Metrics:

Open: 33.01   Previous Close: 33.09
Day Low: —   Day High: —
Year Low:    Year High: 
Price Avg 50:    Price Avg 200: 
Volume:    Average Volume: 

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See in Nexus

Relevant news

Bank of America Corp DE Buys 336,931 Shares of Stoke Therapeutics, Inc. $STOK
20-08-2026 03:24
Bank of America Corp DE Buys 336,931 Shares of Stoke Therapeutics, Inc. $STOK
These Analysts Revise Their Forecasts On Stoke Therapeutics After Q2 Results
04-08-2026 09:28
These Analysts Revise Their Forecasts On Stoke Therapeutics After Q2 Results
Stoke Therapeutics, Inc. (STOK) Q2 2026 Earnings Call Transcript
04-08-2026 05:39
Stoke Therapeutics, Inc. (STOK) Q2 2026 Earnings Call Transcript
Stoke Therapeutics, Inc. (STOK) Reports Q2 Loss, Tops Revenue Estimates
03-08-2026 18:11
Stoke Therapeutics, Inc. (STOK) Reports Q2 Loss, Tops Revenue Estimates
Stoke Therapeutics Q2 Earnings Call Highlights
03-08-2026 18:04
Stoke Therapeutics Q2 Earnings Call Highlights
Stoke Therapeutics, Inc. (STOK) Presents at Goldman Sachs 47th Annual Global Healthcare Conference 2026 Transcript
08-06-2026 13:18
Stoke Therapeutics, Inc. (STOK) Presents at Goldman Sachs 47th Annual Global Healthcare Conference 2026 Transcript

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