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PRAX stock logo

PRAX

Praxis Precision Medicines, Inc.

$250.33
-2.92
 (-1.15%)
Exchange:  NASDAQ
Market Cap:  5.292B
Shares Outstanding:  86509
Delayed data
Calculate PRAX Intrinsic Value
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Overview
Earnings
Financials
Valuation
Chart

About The Company

Sector:  Healthcare
Industry:  Biotechnology
   
CEO:  Marcio Silva De’Souza
Full Time Employees:  116
Address: 
99 High Street
Boston
MA
2110
US
Website:  https://www.praxismedicines.com
Praxis Precision Medicines, Inc. is a biopharmaceutical firm operating at the clinical stage, dedicated to creating innovative treatments for central nervous system (CNS) conditions that stem from an imbalance in neuronal activity. The company’s primary investigational compounds currently undergoing evaluation include: PRAX-114, an extrasynaptic-preferring positive allosteric modulator of the GABAA receptor, which is currently in Phase IIa clinical trials for addressing both major depressive disorder and perimenopausal depression. Additionally, PRAX-944, a small molecule designed to selectively inhibit T-type calcium channels, is also progressing through Phase IIa clinical trials to manage essential tremor. Beyond these, Praxis is also advancing a pipeline of other promising drug candidates, such as: PRAX-562, a persistent sodium current blocker, undergoing Phase I clinical evaluation for treating severe pediatric epilepsy and adult cephalgia (headaches). PRAX-222, an antisense oligonucleotide (ASO) aimed at individuals suffering from gain-of-function (GOF) SCN2A epilepsy. And a program targeting KCNT1 for the treatment of KCNT1 GOF epilepsy. To further its research and development efforts, Praxis maintains several strategic alliances. These include a cooperation and licensing arrangement with RogCon Inc.; a licensing deal with Purdue Neuroscience Company; a comprehensive research collaboration, option, and license agreement with Ionis Pharmaceuticals, Inc.; and a collaborative project with The Florey Institute focused on the creation of three new antisense oligonucleotides (ASOs). Established in 2015, the company’s headquarters are situated in Boston, Massachusetts.

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Revenue Segmentation

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EPS

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Earnings Call

Full text

Earnings transcript

Read the complete earnings call transcript.

AI summary

Key takeaways

Short, structured highlights from the call so you can focus on what matters.

2026/05/09 — Q1 quarter 2026

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Income Statement
Balance Sheet
Cash Flow Statement
Analyst Estimates

Income Statement

Year202320242025
Revenue2,4478,5530
Gross Profit-84,319-143,860-140
EBITDA-125,941-199,807-303,128
Operating Income-126,373-200,165-326,198
Net Income-123,277-182,819-303,268

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(* All numbers are in thousands)

Balance Sheet

Year202320242025
Total Assets87,948483,110937,907
Total Liabilities18,27937,66059,771
Total Stockholders Equity69,669445,450878,136
Total Debt2,4951,369110
Cash and Cash Equivalents81,300215,372357,329

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(* All numbers are in thousands)

Cash Flow Statement

Year202320242025
Operating Cash Flow-111,136-131,757-249,068
Capital Expenditure-500-56
Free Cash Flow-111,186-131,757-249,124
Net Income-123,277-182,819-303,268
Net Change in Cash19,685134,072141,957

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(* All numbers are in thousands)

Analyst Estimates

Fiscal Year2030Full AccessFull AccessFull AccessFull Access
Estimated Revenue (Low)1,637,949.763Full AccessFull AccessFull AccessFull Access
Estimated Revenue (High)5,922,347.020Full AccessFull AccessFull AccessFull Access
Estimated Revenue (Avg)3,507,271.842Full AccessFull AccessFull AccessFull Access
Estimated Ebitda (Low)327,589.952Full AccessFull AccessFull AccessFull Access
Estimated Ebitda (High)1,184,469.403Full AccessFull AccessFull AccessFull Access
Estimated Ebitda (Avg)701,454.368Full AccessFull AccessFull AccessFull Access
Estimated Net Income (Low)367,239.195Full AccessFull AccessFull AccessFull Access
Estimated Net Income (High)2,266,149.859Full AccessFull AccessFull AccessFull Access
Estimated Net Income (Avg)1,195,751.355Full AccessFull AccessFull AccessFull Access
Estimated SGA Expense (Low)8,769,259.450Full AccessFull AccessFull AccessFull Access
Estimated SGA Expense (High)31,707,075.970Full AccessFull AccessFull AccessFull Access
Estimated SGA Expense (Avg)18,777,240.571Full AccessFull AccessFull AccessFull Access
Estimated EPS (Avg)53.130Full AccessFull AccessFull AccessFull Access
Estimated EPS (High)100.700Full AccessFull AccessFull AccessFull Access
Estimated EPS (Low)16.320Full AccessFull AccessFull AccessFull Access
Number of Analysts (Estimated Revenue)7Full AccessFull AccessFull AccessFull Access
Number of Analysts (Estimated EPS)6Full AccessFull AccessFull AccessFull Access

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(* All numbers are in thousands)

Current Key Metrics

?Revenue
 (TTM)
: 
2.447M  ?P/S
 (TTM)
: 
0
?Net Income
 (TTM)
: 
-123277000  ?P/E
 (TTM)
: 
-22.47
?Enterprise Value
 (TTM)
: 
4.835B  ?EV/FCF
 (TTM)
: 
-17.09
?Dividend Yield
 (TTM)
: 
0  ?Payout Ratio
 (TTM)
: 
0
?ROE
 (TTM)
: 
-0.43  ?ROIC
 (TTM)
: 
-0.25
?Net Debt
 (TTM)
: 
-355372000  ?Debt/Equity
 (TTM)
: 
0
?P/B
 (TTM)
: 
5.2  ?Current Ratio
 (TTM)
: 
15.88

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Forward P/E Ratios

?

Forward P/E (Avg EPS estimate) — log in with Full Access for high/low estimates and the interactive table.

Forward P/E 1YFull AccessFull AccessFull AccessFull Access
N/AFull AccessFull AccessFull AccessFull Access

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SWOT Analysis

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At what price to buy it? -
Intrinsic Value Calculator

This is an automatic estimate. The most reliable way to know fair value for your own assumptions is to run the calculator below.

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Common questions about PRAX valuation

Is Praxis Precision Medicines, Inc. (PRAX) overvalued or undervalued right now?

MARKETSnap estimates intrinsic value for Praxis Precision Medicines, Inc. (PRAX) using its proprietary valuation methodology, which incorporates discounted cash flow (DCF) analysis together with long-term earnings and fundamentals assumptions. By comparing intrinsic value to the current market price, long-term investors can see whether the stock screens as potentially overvalued, fairly valued, or undervalued today.

Is PRAX a buy, hold, or sell for long-term investors?

MARKETSnap does not give one-word “buy” or “sell” calls. Instead, it shows whether PRAX trades at a premium or discount to its estimated intrinsic value, how sensitive that value is to growth and margin assumptions, and how the stock fits into a diversified, long-term portfolio so investors can make their own buy, hold, or sell decision.

What is PRAX’s P/E ratio?

You can see PRAX’s trailing P/E (TTM) and forward P/E estimates in the Current Key Metrics and Forward P/E Ratios sections above. The P/E ratio compares the current share price to earnings per share and helps investors gauge valuation relative to earnings.

How is intrinsic value calculated for PRAX?

MARKETSnap uses its own valuation framework—not a generic spreadsheet DCF alone. Future cash flows and earnings are projected, discounted, and combined with MARKETSnap’s methodology so intrinsic value reflects fundamentals and long-term assumptions. You can run your own inputs and see the result using the Intrinsic Value Calculator above.

Is PRAX a good long-term investment?

Whether PRAX fits a long-term portfolio depends on your assumptions about growth, margins, and risk. MARKETSnap provides the metrics, intrinsic value calculator, and SWOT context so you can form your own view rather than rely on a single buy/sell rating.

PRAX

1-day price chart preview. Log in for 1W through 5Y ranges and period tabs.

Daily snapshot

-1.15
MARKETSnap

Trading Metrics:

Open: 260.43   Previous Close: 253.25
Day Low: 244.16   Day High: 266.6
Year Low: 37.19   Year High: 366.52
Price Avg 50: 323.54   Price Avg 200: 236.77
Volume: 426392   Average Volume: 418177

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See in Nexus

Relevant news

Praxis Precision Medicines, Inc. (PRAX) Presents at Goldman Sachs 47th Annual Global Healthcare Conference 2026 Transcript
08-06-2026 16:38
Praxis Precision Medicines, Inc. (PRAX) Presents at Goldman Sachs 47th Annual Global Healthcare Conference 2026 Transcript
Praxis' Premium Price May Reflect Unrealistic Market Prospects In Essential Tremor
05-06-2026 15:23
Praxis' Premium Price May Reflect Unrealistic Market Prospects In Essential Tremor
Praxis Reassesses Vormatrigine Program After Pivotal Epilepsy Study Misses Primary Endpoint
02-06-2026 06:09
Praxis Reassesses Vormatrigine Program After Pivotal Epilepsy Study Misses Primary Endpoint
Praxis Precision's epilepsy drug misses main goal of mid-to-late stage study
01-06-2026 18:11
Praxis Precision's epilepsy drug misses main goal of mid-to-late stage study
Praxis Precision Medicines, Inc. (PRAX) Presents at Bank of America Global Healthcare Conference 2026 Prepared Remarks Transcript
12-05-2026 21:30
Praxis Precision Medicines, Inc. (PRAX) Presents at Bank of America Global Healthcare Conference 2026 Prepared Remarks Transcript
Praxis Precision Medicines Q1 Earnings Call Highlights
08-05-2026 16:15
Praxis Precision Medicines Q1 Earnings Call Highlights

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