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AXSM stock logo

AXSM

Axsome Therapeutics, Inc.

$168.51
-3.28
 (-1.91%)
[ms_data_label text=’Delayed data’]
Exchange:  NASDAQ
Market Cap:  8.62B
Shares Outstanding:  12.718M
Overview
Earnings
Financials
Valuation
Chart

About The Company

Sector:  Healthcare
Industry:  Biotechnology
   
CEO:  Herriot Tabuteau
Full Time Employees:  712
Address: 
22 Cortlandt Street
New York City
NY
10007
US
Website:  https://www.axsome.com
Axsome Therapeutics, Inc., a biopharmaceutical company, engages in the development of novel therapies for central nervous system (CNS) disorders in the United States. The company’s product pipeline includes AXS-05, a therapeutic for the treatment of major depressive disorder and resistant depression disorders; and that is in the Phase III clinical trial to treat Alzheimer’s disease agitation, as well as that has completed phase II clinical trial for the treatment of smoking cessation. It is also developing AXS-07, a novel, oral, rapidly absorbed, multi-mechanistic, and investigational medicine that has completed two Phase III trials for the acute treatment of migraine; AXS-12, a selective and potent norepinephrine reuptake inhibitor, which is in Phase III trial to treat narcolepsy; and AXS-14, a novel, oral, and investigational medicine that is in Phase III trial for the treatment of fibromyalgia. Axsome Therapeutics, Inc. has a research collaboration agreement with Duke University for evaluating AXS-05 in smoking cessation. The company was incorporated in 2012 and is based in New York, New York.

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Revenue Segmentation

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EPS

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Earnings Call

Full text

Earnings transcript

Read the complete earnings call transcript.

AI summary

Key takeaways

Short, structured highlights from the call so you can focus on what matters.

2025/05/05 — Q1 quarter 2025

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Income Statement
Balance Sheet
Cash Flow Statement
Analyst Estimates

Income Statement

Year202320242025
Revenue270,600385,693638,496
Gross Profit244,535352,390591,018
EBITDA-224,991-272,604-168,083
Operating Income-231,825-280,562-169,235
Net Income-239,238-287,216-183,174

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(* All numbers are in thousands)

Balance Sheet

Year202320242025
Total Assets588,236568,498689,805
Total Liabilities397,259511,483601,510
Total Stockholders Equity190,97757,01588,295
Total Debt186,372192,955215,568
Cash and Cash Equivalents386,193315,353322,933

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(* All numbers are in thousands)

Cash Flow Statement

Year202320242025
Operating Cash Flow-145,080-128,410-93,405
Capital Expenditure-582-2700
Free Cash Flow-145,662-128,680-93,405
Net Income-239,238-287,216-183,174
Net Change in Cash185,351-70,8407,580

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(* All numbers are in thousands)

Analyst Estimates

Fiscal Year2030Full AccessFull AccessFull AccessFull Access
Estimated Revenue (Low)2,790,535.250Full AccessFull AccessFull AccessFull Access
Estimated Revenue (High)3,935,488.214Full AccessFull AccessFull AccessFull Access
Estimated Revenue (Avg)3,321,451.176Full AccessFull AccessFull AccessFull Access
Estimated Ebitda (Low)-1,417,949.134Full AccessFull AccessFull AccessFull Access
Estimated Ebitda (High)-1,005,424.696Full AccessFull AccessFull AccessFull Access
Estimated Ebitda (Avg)-1,196,712.723Full AccessFull AccessFull AccessFull Access
Estimated Net Income (Low)1,061,061.063Full AccessFull AccessFull AccessFull Access
Estimated Net Income (High)1,661,276.696Full AccessFull AccessFull AccessFull Access
Estimated Net Income (Avg)1,339,381.605Full AccessFull AccessFull AccessFull Access
Estimated SGA Expense (Low)4,094,847.766Full AccessFull AccessFull AccessFull Access
Estimated SGA Expense (High)5,774,958.450Full AccessFull AccessFull AccessFull Access
Estimated SGA Expense (Avg)4,873,916.905Full AccessFull AccessFull AccessFull Access
Estimated EPS (Avg)26.920Full AccessFull AccessFull AccessFull Access
Estimated EPS (High)33.390Full AccessFull AccessFull AccessFull Access
Estimated EPS (Low)21.330Full AccessFull AccessFull AccessFull Access
Number of Analysts (Estimated Revenue)13Full AccessFull AccessFull AccessFull Access
Number of Analysts (Estimated EPS)5Full AccessFull AccessFull AccessFull Access

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(* All numbers are in thousands)

Current Key Metrics

?Revenue
 (TTM)
: 
385.693M  ?P/S
 (TTM)
: 
15.14
?Net Income
 (TTM)
: 
-287216000  ?P/E
 (TTM)
: 
-52.24
?Enterprise Value
 (TTM)
: 
9.586B  ?EV/FCF
 (TTM)
: 
-102.1
?Dividend Yield
 (TTM)
: 
0  ?Payout Ratio
 (TTM)
: 
0
?ROE
 (TTM)
: 
-2.54  ?ROIC
 (TTM)
: 
-0.44
?Net Debt
 (TTM)
: 
-112440000  ?Debt/Equity
 (TTM)
: 
2.73
?P/B
 (TTM)
: 
108.37  ?Current Ratio
 (TTM)
: 
1.55

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Forward P/E Ratios

?

Forward P/E (Avg EPS estimate) — log in with Full Access for high/low estimates and the interactive table.

Forward P/E 1YFull AccessFull AccessFull AccessFull Access
N/AFull AccessFull AccessFull AccessFull Access

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SWOT Analysis

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Intrinsic Value Calculator

This is an automatic estimate. The most reliable way to know fair value for your own assumptions is to run the calculator below.


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Common questions about AXSM valuation

Is Axsome Therapeutics, Inc. (AXSM) overvalued or undervalued right now?

MARKETSnap estimates intrinsic value for Axsome Therapeutics, Inc. (AXSM) using its proprietary valuation methodology, which incorporates discounted cash flow (DCF) analysis together with long-term earnings and fundamentals assumptions. By comparing intrinsic value to the current market price, long-term investors can see whether the stock screens as potentially overvalued, fairly valued, or undervalued today.

Is AXSM a buy, hold, or sell for long-term investors?

MARKETSnap does not give one-word “buy” or “sell” calls. Instead, it shows whether AXSM trades at a premium or discount to its estimated intrinsic value, how sensitive that value is to growth and margin assumptions, and how the stock fits into a diversified, long-term portfolio so investors can make their own buy, hold, or sell decision.

What is AXSM’s P/E ratio?

You can see AXSM’s trailing P/E (TTM) and forward P/E estimates in the Current Key Metrics and Forward P/E Ratios sections above. The P/E ratio compares the current share price to earnings per share and helps investors gauge valuation relative to earnings.

How is intrinsic value calculated for AXSM?

MARKETSnap uses its own valuation framework—not a generic spreadsheet DCF alone. Future cash flows and earnings are projected, discounted, and combined with MARKETSnap’s methodology so intrinsic value reflects fundamentals and long-term assumptions. You can run your own inputs and see the result using the Intrinsic Value Calculator above.

Is AXSM a good long-term investment?

Whether AXSM fits a long-term portfolio depends on your assumptions about growth, margins, and risk. MARKETSnap provides the metrics, intrinsic value calculator, and SWOT context so you can form your own view rather than rely on a single buy/sell rating.

AXSM

1-day price chart preview. Log in for 1W through 5Y ranges and period tabs.

[ms_data_label text="Daily snapshot"]

-1.91
MARKETSnap

Trading Metrics:

[ms_session_rows_unavailable]
Open: [ms_cell_or_dash table='trading_quote' column='open']   Previous Close: [ms_cell_or_dash table='trading_quote' column='previousClose']
Day Low: [ms_cell_or_dash table='trading_quote' column='dayLow']   Day High: [ms_cell_or_dash table='trading_quote' column='dayHigh']
Year Low: 86.99   Year High: 191.5
Price Avg 50: 171.88   Price Avg 200: 139.73
Volume: 525975   Average Volume: 638872

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See in Nexus

Relevant news

Axsome Therapeutics, Inc. (AXSM) Discusses Approval of AUVELITY for Agitation Associated With Dementia Due to Alzheimer's Disease Transcript
01-05-2026 16:31
Axsome Therapeutics, Inc. (AXSM) Discusses Approval of AUVELITY for Agitation Associated With Dementia Due to Alzheimer's Disease Transcript
Axsome Therapeutics, Inc. (NASDAQ:AXSM) Given Average Rating of “Moderate Buy” by Brokerages
10-04-2026 03:18
Axsome Therapeutics, Inc. (NASDAQ:AXSM) Given Average Rating of “Moderate Buy” by Brokerages
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Why Is Axsome (AXSM) Down 6.6% Since Last Earnings Report?
25-03-2026 12:31
Why Is Axsome (AXSM) Down 6.6% Since Last Earnings Report?
AXSM's 2025 Revenue Surge Largely Driven by Auvelity: What's Ahead?
13-03-2026 12:41
AXSM's 2025 Revenue Surge Largely Driven by Auvelity: What's Ahead?
Axsome Therapeutics, Inc. (AXSM) Presents at The Citizens Life Sciences Conference 2026 Transcript
13-03-2026 03:52
Axsome Therapeutics, Inc. (AXSM) Presents at The Citizens Life Sciences Conference 2026 Transcript

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