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ANNX stock logo

ANNX

Annexon, Inc.

$5.2
0.08
 (1.56%)
Exchange:  NASDAQ
Market Cap:  621.894M
Shares Outstanding:  38.221M
Delayed data
Calculate ANNX Intrinsic Value
5-year outlook →
Overview
Earnings
Financials
Valuation
Chart

About The Company

Sector:  Healthcare
Industry:  Biotechnology
   
CEO:  Douglas E. Love
Full Time Employees:  106
Address: 
1400 Sierra Point Parkway
Brisbane
CA
94005
US
Website:  https://www.annexonbio.com
Annexon, Inc. is a biopharmaceutical company currently engaged in clinical trials, dedicated to the discovery and advancement of therapies for a variety of autoimmune, neurodegenerative, and ophthalmic conditions. Central to its approach is the C1q molecule, which initiates the classical complement pathway. The company targets this pathway to address specific disease mechanisms, such as those seen in antibody-mediated autoimmune disorders and complement-driven neurodegeneration. The company’s developmental pipeline features several promising candidates. ANX005, a monoclonal antibody, is in advanced clinical testing, undergoing Phase II/III trials for Guillain-Barré syndrome, as well as Phase II trials for warm autoimmune hemolytic anemia, Huntington’s disease, and amyotrophic lateral sclerosis. Another candidate, ANX009, is currently in Phase Ib studies for lupus nephritis. Additionally, ANX007 is progressing through Phase II clinical trials for the treatment of geographic atrophy, an eye disease. Further investigational assets include ANX105, a monoclonal antibody being developed for neurodegenerative indications, and ANX1502, an oral small molecule under investigation for specific autoimmune conditions. Annexon, Inc. was established in 2011 and operates from its headquarters in Brisbane, California.

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Revenue Segmentation

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EPS

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Earnings Call

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Income Statement
Balance Sheet
Cash Flow Statement
Analyst Estimates

Income Statement

Year202320242025
Revenue000
Gross Profit0-3,454-3,686
EBITDA-141,575-134,746-213,757
Operating Income-143,723-154,073-216,407
Net Income-134,237-138,200-206,690

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(* All numbers are in thousands)

Balance Sheet

Year202320242025
Total Assets297,674350,071277,571
Total Liabilities47,11856,96665,923
Total Stockholders Equity250,556293,105211,648
Total Debt31,35528,97226,201
Cash and Cash Equivalents225,11049,498162,051

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(* All numbers are in thousands)

Cash Flow Statement

Year202320242025
Operating Cash Flow-121,142-118,006-186,356
Capital Expenditure-193-15-137
Free Cash Flow-121,335-118,021-186,493
Net Income-134,237-138,200-206,690
Net Change in Cash85,090-175,612112,551

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(* All numbers are in thousands)

Analyst Estimates

Fiscal Year2030Full AccessFull AccessFull AccessFull Access
Estimated Revenue (Low)188,866.075Full AccessFull AccessFull AccessFull Access
Estimated Revenue (High)2,615,036.794Full AccessFull AccessFull AccessFull Access
Estimated Revenue (Avg)1,060,752.332Full AccessFull AccessFull AccessFull Access
Estimated Ebitda (Low)0Full AccessFull AccessFull AccessFull Access
Estimated Ebitda (High)0Full AccessFull AccessFull AccessFull Access
Estimated Ebitda (Avg)0Full AccessFull AccessFull AccessFull Access
Estimated Net Income (Low)-28,688.374Full AccessFull AccessFull AccessFull Access
Estimated Net Income (High)1,215,913.401Full AccessFull AccessFull AccessFull Access
Estimated Net Income (Avg)418,581.009Full AccessFull AccessFull AccessFull Access
Estimated SGA Expense (Low)0Full AccessFull AccessFull AccessFull Access
Estimated SGA Expense (High)0Full AccessFull AccessFull AccessFull Access
Estimated SGA Expense (Avg)0Full AccessFull AccessFull AccessFull Access
Estimated EPS (Avg)2.700Full AccessFull AccessFull AccessFull Access
Estimated EPS (High)7.840Full AccessFull AccessFull AccessFull Access
Estimated EPS (Low)-0.180Full AccessFull AccessFull AccessFull Access
Number of Analysts (Estimated Revenue)6Full AccessFull AccessFull AccessFull Access
Number of Analysts (Estimated EPS)2Full AccessFull AccessFull AccessFull Access

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(* All numbers are in thousands)

Current Key Metrics

?Revenue
 (TTM)
: 
0  ?P/S
 (TTM)
: 
0
?Net Income
 (TTM)
: 
-134237000  ?P/E
 (TTM)
: 
-5.23
?Enterprise Value
 (TTM)
: 
482.884M  ?EV/FCF
 (TTM)
: 
-2.64
?Dividend Yield
 (TTM)
: 
0  ?Payout Ratio
 (TTM)
: 
-0.01
?ROE
 (TTM)
: 
-1.01  ?ROIC
 (TTM)
: 
-0.89
?Net Debt
 (TTM)
: 
-310509000  ?Debt/Equity
 (TTM)
: 
0.12
?P/B
 (TTM)
: 
5.02  ?Current Ratio
 (TTM)
: 
6.35

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Forward P/E Ratios

?

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Forward P/E 1YFull AccessFull AccessFull AccessFull Access
N/AFull AccessFull AccessFull AccessFull Access

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SWOT Analysis

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At what price to buy it? -
Intrinsic Value Calculator

This is an automatic estimate. The most reliable way to know fair value for your own assumptions is to run the calculator below.

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Common questions about ANNX valuation

Is Annexon, Inc. (ANNX) overvalued or undervalued right now?

MARKETSnap estimates intrinsic value for Annexon, Inc. (ANNX) using its proprietary valuation methodology, which incorporates discounted cash flow (DCF) analysis together with long-term earnings and fundamentals assumptions. By comparing intrinsic value to the current market price, long-term investors can see whether the stock screens as potentially overvalued, fairly valued, or undervalued today.

Is ANNX a buy, hold, or sell for long-term investors?

MARKETSnap does not give one-word “buy” or “sell” calls. Instead, it shows whether ANNX trades at a premium or discount to its estimated intrinsic value, how sensitive that value is to growth and margin assumptions, and how the stock fits into a diversified, long-term portfolio so investors can make their own buy, hold, or sell decision.

What is ANNX’s P/E ratio?

You can see ANNX’s trailing P/E (TTM) and forward P/E estimates in the Current Key Metrics and Forward P/E Ratios sections above. The P/E ratio compares the current share price to earnings per share and helps investors gauge valuation relative to earnings.

How is intrinsic value calculated for ANNX?

MARKETSnap uses its own valuation framework—not a generic spreadsheet DCF alone. Future cash flows and earnings are projected, discounted, and combined with MARKETSnap’s methodology so intrinsic value reflects fundamentals and long-term assumptions. You can run your own inputs and see the result using the Intrinsic Value Calculator above.

Is ANNX a good long-term investment?

Whether ANNX fits a long-term portfolio depends on your assumptions about growth, margins, and risk. MARKETSnap provides the metrics, intrinsic value calculator, and SWOT context so you can form your own view rather than rely on a single buy/sell rating.

ANNX

1-day price chart preview. Log in for 1W through 5Y ranges and period tabs.

Daily snapshot

1.56
MARKETSnap

Trading Metrics:

Open: 5.19   Previous Close: 5.12
Day Low: 5.02   Day High: 5.34
Year Low: 1.85   Year High: 7.18
Price Avg 50: 5.65   Price Avg 200: 4.62
Volume: 3.167M   Average Volume: 2.503M

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See in Nexus

Relevant news

Annexon Maps 3 Big Pipeline Catalysts Ahead of Q4 Vision-Drug Readout
04-06-2026 03:07
Annexon Maps 3 Big Pipeline Catalysts Ahead of Q4 Vision-Drug Readout
Annexon Reports Inducement Grants to New Employees Under Nasdaq Listing Rule 5635(c)(4)
16-01-2026 17:05
Annexon Reports Inducement Grants to New Employees Under Nasdaq Listing Rule 5635(c)(4)
Annexon Highlights Q4 Geographic Atrophy Data, GBS Filing Plans at BofA Conference
14-05-2026 04:06
Annexon Highlights Q4 Geographic Atrophy Data, GBS Filing Plans at BofA Conference
Annexon, Inc. (ANNX) Presents at Bank of America Global Healthcare Conference 2026 Transcript
13-05-2026 17:10
Annexon, Inc. (ANNX) Presents at Bank of America Global Healthcare Conference 2026 Transcript
Annexon CEO Touts “Win Year” 2026 at Needham, Eyes GA Phase III Data and GBS FDA Filing
17-04-2026 03:31
Annexon CEO Touts “Win Year” 2026 at Needham, Eyes GA Phase III Data and GBS FDA Filing
Annexon to Present at the 25th Annual Needham Virtual Healthcare Conference
08-04-2026 16:05
Annexon to Present at the 25th Annual Needham Virtual Healthcare Conference

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