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KRYS stock logo

KRYS

Krystal Biotech, Inc.

$314.64
4.89
 (1.58%)
Exchange:  NASDAQ
Market Cap:  9.276B
Shares Outstanding:  4.275M
Delayed data
Calculate KRYS Intrinsic Value
5-year outlook →
Overview
Earnings
Financials
Valuation
Chart

About The Company

Sector:  Healthcare
Industry:  Biotechnology
   
CEO:  Krish S. Krishnan
Full Time Employees:  275
Address: 
2100 Wharton Street
Pittsburgh
PA
15203
US
Website:  https://www.krystalbio.com
Krystal Biotech, Inc. is a clinical-stage biotechnology company focused on developing redosable gene therapies to address severe orphan diseases across the United States. Its most advanced therapeutic candidate, beremagene geperpavec (B-VEC), is currently undergoing Phase III clinical evaluation for the treatment of dystrophic epidermolysis bullosa. The company’s pipeline also includes several other promising programs: KB105 is in Phase I/II clinical trials for patients suffering from deficient autosomal recessive congenital ichthyosis; KB301 is also in Phase I/II development, aiming to ameliorate wrinkles and other signs of aging or damaged skin. Additionally, Krystal Biotech is conducting preclinical research on KB407 for cystic fibrosis and KB104 for Netherton syndrome. In its earlier discovery phase, the company is exploring candidates such as KB5xx for chronic skin conditions and multiple KB3xx programs targeting aesthetic dermatological concerns. Krystal Biotech, Inc. was established in 2015 and is based in Pittsburgh, Pennsylvania.

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Revenue Segmentation

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EPS

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Earnings Call

Full text

Earnings transcript

Read the complete earnings call transcript.

AI summary

Key takeaways

Short, structured highlights from the call so you can focus on what matters.

2026/05/04 — Q1 quarter 2026

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Income Statement
Balance Sheet
Cash Flow Statement
Analyst Estimates

Income Statement

Year202320242025
Revenue50,699290,515389,130
Gross Profit47,605270,454360,357
EBITDA-91,316109,909167,846
Operating Income-109,72765,695161,295
Net Income10,93289,159204,831

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(* All numbers are in thousands)

Balance Sheet

Year202320242025
Total Assets818,3551,055,8381,333,794
Total Liabilities39,714109,458114,234
Total Stockholders Equity778,641946,3801,219,560
Total Debt8,0947,2611,771
Cash and Cash Equivalents358,328344,865496,304

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(* All numbers are in thousands)

Cash Flow Statement

Year202320242025
Operating Cash Flow-88,804123,420200,865
Capital Expenditure-11,799-4,238-11,951
Free Cash Flow-100,603119,182188,914
Net Income10,93289,159204,831
Net Change in Cash196,428-13,463151,439

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(* All numbers are in thousands)

Analyst Estimates

Fiscal Year2030Full AccessFull AccessFull AccessFull Access
Estimated Revenue (Low)1,637,007.478Full AccessFull AccessFull AccessFull Access
Estimated Revenue (High)1,820,296.685Full AccessFull AccessFull AccessFull Access
Estimated Revenue (Avg)1,726,800Full AccessFull AccessFull AccessFull Access
Estimated Ebitda (Low)592,485.806Full AccessFull AccessFull AccessFull Access
Estimated Ebitda (High)658,824.082Full AccessFull AccessFull AccessFull Access
Estimated Ebitda (Avg)624,984.616Full AccessFull AccessFull AccessFull Access
Estimated Net Income (Low)973,009.483Full AccessFull AccessFull AccessFull Access
Estimated Net Income (High)1,117,006.109Full AccessFull AccessFull AccessFull Access
Estimated Net Income (Avg)1,043,552.776Full AccessFull AccessFull AccessFull Access
Estimated SGA Expense (Low)1,541,835.908Full AccessFull AccessFull AccessFull Access
Estimated SGA Expense (High)1,714,469.133Full AccessFull AccessFull AccessFull Access
Estimated SGA Expense (Avg)1,626,408.114Full AccessFull AccessFull AccessFull Access
Estimated EPS (Avg)34.840Full AccessFull AccessFull AccessFull Access
Estimated EPS (High)37.290Full AccessFull AccessFull AccessFull Access
Estimated EPS (Low)32.490Full AccessFull AccessFull AccessFull Access
Number of Analysts (Estimated Revenue)3Full AccessFull AccessFull AccessFull Access
Number of Analysts (Estimated EPS)1Full AccessFull AccessFull AccessFull Access

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(* All numbers are in thousands)

Current Key Metrics

?Revenue
 (TTM)
: 
290.515M  ?P/S
 (TTM)
: 
21.26
?Net Income
 (TTM)
: 
89.159M  ?P/E
 (TTM)
: 
39.18
?Enterprise Value
 (TTM)
: 
8.374B  ?EV/FCF
 (TTM)
: 
35.28
?Dividend Yield
 (TTM)
: 
0  ?Payout Ratio
 (TTM)
: 
0
?ROE
 (TTM)
: 
0.19  ?ROIC
 (TTM)
: 
0.14
?Net Debt
 (TTM)
: 
-590256000  ?Debt/Equity
 (TTM)
: 
0
?P/B
 (TTM)
: 
6.9  ?Current Ratio
 (TTM)
: 
9.46

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Forward P/E Ratios

?

Forward P/E (Avg EPS estimate) — log in with Full Access for high/low estimates and the interactive table.

Forward P/E 1YFull AccessFull AccessFull AccessFull Access
40.60Full AccessFull AccessFull AccessFull Access

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SWOT Analysis

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At what price to buy it? -
Intrinsic Value Calculator

Based on current fundamentals and analyst forecasts, MARKETSnap estimates KRYS intrinsic value between $58.97 – $770.31 per share. This depends on revenue growth, margins, and discount rate.

This is an automatic estimate. The most reliable way to know fair value for your own assumptions is to run the calculator below.

[intrinsic_calculator]

Common questions about KRYS valuation

Is Krystal Biotech, Inc. (KRYS) overvalued or undervalued right now?

MARKETSnap estimates intrinsic value for Krystal Biotech, Inc. (KRYS) using its proprietary valuation methodology, which incorporates discounted cash flow (DCF) analysis together with long-term earnings and fundamentals assumptions. By comparing intrinsic value to the current market price, long-term investors can see whether the stock screens as potentially overvalued, fairly valued, or undervalued today.

Is KRYS a buy, hold, or sell for long-term investors?

MARKETSnap does not give one-word “buy” or “sell” calls. Instead, it shows whether KRYS trades at a premium or discount to its estimated intrinsic value, how sensitive that value is to growth and margin assumptions, and how the stock fits into a diversified, long-term portfolio so investors can make their own buy, hold, or sell decision.

What is KRYS’s P/E ratio?

You can see KRYS’s trailing P/E (TTM) and forward P/E estimates in the Current Key Metrics and Forward P/E Ratios sections above. The P/E ratio compares the current share price to earnings per share and helps investors gauge valuation relative to earnings.

How is intrinsic value calculated for KRYS?

MARKETSnap uses its own valuation framework—not a generic spreadsheet DCF alone. Future cash flows and earnings are projected, discounted, and combined with MARKETSnap’s methodology so intrinsic value reflects fundamentals and long-term assumptions. You can run your own inputs and see the result using the Intrinsic Value Calculator above.

Is KRYS a good long-term investment?

Whether KRYS fits a long-term portfolio depends on your assumptions about growth, margins, and risk. MARKETSnap provides the metrics, intrinsic value calculator, and SWOT context so you can form your own view rather than rely on a single buy/sell rating.

KRYS

1-day price chart preview. Log in for 1W through 5Y ranges and period tabs.

Daily snapshot

1.58
MARKETSnap

Trading Metrics:

Open: 309.75   Previous Close: 309.75
Day Low: 309.45   Day High: 320.32
Year Low: 127.99   Year High: 320.38
Price Avg 50: 283.25   Price Avg 200: 237.12
Volume: 129599   Average Volume: 278895

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See in Nexus

Relevant news

Is the Options Market Predicting a Spike in Krystal Biotech Stock?
05-06-2026 13:00
Is the Options Market Predicting a Spike in Krystal Biotech Stock?
Krystal Biotech, Inc. (KRYS) Presents at Bank of America Global Healthcare Conference 2026 Transcript
13-05-2026 16:40
Krystal Biotech, Inc. (KRYS) Presents at Bank of America Global Healthcare Conference 2026 Transcript
This Profitable Biotech Stealthily Climbs Into A Buy Zone
11-05-2026 14:15
This Profitable Biotech Stealthily Climbs Into A Buy Zone
Krystal Biotech Analysts Boost Their Forecasts Following Upbeat Q1 Results
05-05-2026 14:19
Krystal Biotech Analysts Boost Their Forecasts Following Upbeat Q1 Results
Krystal Biotech Q1 Earnings & Sales Beat Estimates, Pipeline in Focus
05-05-2026 14:00
Krystal Biotech Q1 Earnings & Sales Beat Estimates, Pipeline in Focus
Krystal Biotech, Inc. (KRYS) Q1 2026 Earnings Call Transcript
04-05-2026 13:43
Krystal Biotech, Inc. (KRYS) Q1 2026 Earnings Call Transcript

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