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CNTA

CNTA

Centessa Pharmaceuticals plc

$40.5
0
 (0%)
Exchange:  NASDAQ
Market Cap:  6.267B
Shares Outstanding:  70.891M
Delayed data
Overview
Earnings
Financials
Valuation
Chart

About The Company

Sector:  HealthcareView sector performance
Industry:  BiotechnologyView industry performance
   
CEO:  Mario Alberto Accardi
Full Time Employees:  129
Address: 
1 Ashley Road
Altrincham
WA14 2DT
GB
Website:  https://www.centessa.com
Centessa Pharmaceuticals plc operates as a clinical-stage pharmaceutical enterprise focused on discovering, developing, and ultimately providing therapeutic solutions to patients. The company’s most advanced product candidates include Lixivaptan, a small molecule inhibitor of the vasopressin V2 receptor, which is currently undergoing Phase III clinical evaluation for treating autosomal dominant polycystic kidney disease. Additionally, SerpinPC, an activated protein C inhibitor, is progressing through Phase IIa clinical development for the management of hemophilia A and B. Centessa’s pipeline also features several emerging assets in the clinical proof-of-concept stage. These comprise LB101 (a PD-L1xCD47 LockBody) and LB201 (a PD-L1xCD3 LockBody), both engineered to selectively activate potent CD47 and CD3 effector functions while minimizing systemic side effects. Another molecule, ZF874, is a small molecule pharmacological chaperone in Phase I studies, designed to correct the misfolding of the Z variant of alpha-1-antitrypsin, thus addressing alpha-1-antitrypsin deficiency. Furthermore, MGX292, a recombinant modified BMP9 replacement protein, aims to rectify the deficient BMP9 signaling implicated in Pulmonary Arterial Hypertension. The company is also developing OX2R Agonists, which are selective orexin receptor 2 agonists (available as oral and intranasal formulations) intended to directly target the underlying pathophysiology of orexin neuron loss in Narcolepsy Type 1 by leveraging structural insights. Beyond these, Centessa is exploring further clinical proof-of-concept compounds. CBS001, an anti-LIGHT antibody, is being investigated for inflammatory and fibrotic diseases due to its preferential binding to the inflammatory membrane form of LIGHT. Lastly, CBS004 is a humanized monoclonal antibody specifically targeting BDCA2, a protein found exclusively on plasmacytoid dendritic cells, with potential utility in conditions such as systemic sclerosis, systemic lupus erythematosus, and other autoimmune disorders. Centessa Pharmaceuticals plc was established in 2020 and is headquartered in Altrincham, United Kingdom.

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Revenue Segmentation

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CNTA full analysis

31/03/2026

Hey everyone, welcome back to the channel! Today, we’re diving deep into a comprehensive analysis of Centessa Pharmaceuticals, ticker symbol CNTA, a clinical-stage biotech company that’s been making some serious waves lately. Whether you’re a seasoned investor or just curious about the biotech space, stick around because we’re going to unpack everything from financials to future potential. Let’s get started! So, first off, why are we talking about Centessa? Well, this company is in the healthcare sector, specifically in biotechnology,…

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Industry Peers

TICKERCOMPANYMKT CAPP/EFWD P/EROIC
CNCNTA logoCNTACentessa Pharmaceuticals plc6.3B——-42.4%
IOIOVA logoIOVAIovance Biotherapeutics, Inc.6.2B——-36.0%
ABABVX logoABVXAbivax S.A.6.5B——-61.0%
RYRYTM logoRYTMRhythm Pharmaceuticals, Inc.5.9B——-63.8%
LGLGND logoLGNDLigand Pharmaceuticals Incorporated5.9B30.231.73.9%
PRPRAX logoPRAXPraxis Precision Medicines, Inc.6.7B——-28.2%

EPS

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Earnings Call

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Income Statement
Balance Sheet
Cash Flow Statement
Analyst Estimates

Income Statement

Year202320242025
Revenue6,853015,000
Gross Profit6,853015,000
EBITDA-165,425-221,881-183,333
Operating Income-171,283-201,055-207,692
Net Income-151,085-235,757-197,532

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(* All numbers are in thousands)

Balance Sheet

Year202320242025
Total Assets360,246576,798687,495
Total Liabilities124,002175,253160,632
Total Stockholders Equity236,244401,545526,863
Total Debt84,588117,2267,573
Cash and Cash Equivalents128,030383,22161,299

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(* All numbers are in thousands)

Cash Flow Statement

Year202320242025
Operating Cash Flow-160,963.497-142,055-193,817
Capital Expenditure-169.655-34-371
Free Cash Flow-161,133.152-142,089-194,188
Net Income-151,670.616-235,757-197,532
Net Change in Cash-265,614255,191-321,268

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(* All numbers are in thousands)

Analyst Estimates

Fiscal Year2030Research AccessResearch AccessResearch AccessResearch Access
Estimated Revenue (Low)882,550Research AccessResearch AccessResearch AccessResearch Access
Estimated Revenue (High)882,550Research AccessResearch AccessResearch AccessResearch Access
Estimated Revenue (Avg)882,550Research AccessResearch AccessResearch AccessResearch Access
Estimated Ebitda (Low)471,732.295Research AccessResearch AccessResearch AccessResearch Access
Estimated Ebitda (High)471,732.295Research AccessResearch AccessResearch AccessResearch Access
Estimated Ebitda (Avg)471,732.295Research AccessResearch AccessResearch AccessResearch Access
Estimated Net Income (Low)361,908.743Research AccessResearch AccessResearch AccessResearch Access
Estimated Net Income (High)361,908.743Research AccessResearch AccessResearch AccessResearch Access
Estimated Net Income (Avg)361,908.743Research AccessResearch AccessResearch AccessResearch Access
Estimated SGA Expense (Low)2,507,331.811Research AccessResearch AccessResearch AccessResearch Access
Estimated SGA Expense (High)2,507,331.811Research AccessResearch AccessResearch AccessResearch Access
Estimated SGA Expense (Avg)2,507,331.811Research AccessResearch AccessResearch AccessResearch Access
Estimated EPS (Avg)2.670Research AccessResearch AccessResearch AccessResearch Access
Estimated EPS (High)2.670Research AccessResearch AccessResearch AccessResearch Access
Estimated EPS (Low)2.670Research AccessResearch AccessResearch AccessResearch Access
Number of Analysts (Estimated Revenue)3Research AccessResearch AccessResearch AccessResearch Access
Number of Analysts (Estimated EPS)2Research AccessResearch AccessResearch AccessResearch Access

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(* All numbers are in thousands)

Current Key Metrics

?Revenue
 (TTM)
: 
0  ?P/S
 (TTM)
: 
0
?Net Income
 (TTM)
: 
-235.856M  ?P/E
 (TTM)
: 
-22.75
?Enterprise Value
 (TTM)
: 
6.212B  ?EV/FCF
 (TTM)
: 
-29.7
?Dividend Yield
 (TTM)
: 
0%  ?Payout Ratio
 (TTM)
: 
0%
?ROE
 (TTM)
: 
-60.37%  ?ROIC
 (TTM)
: 
-42.42%
?Net Debt
 (TTM)
: 
-364.951M  ?Debt/Equity
 (TTM)
: 
0.02
?P/B
 (TTM)
: 
12.76  ?Current Ratio
 (TTM)
: 
9.53

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Forward P/E Ratios

?

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Forward P/E 1YResearch AccessResearch AccessResearch AccessResearch Access
N/AResearch AccessResearch AccessResearch AccessResearch Access

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SWOT Analysis

Strengths (preview)

  • Solid Financial Position: CNTA demonstrates a healthy balance sheet with significant cash and cash equivalents, as indicated by the Balance Sheet data. A strong current ratio (currentRatioTTM) and quick ratio (quickRatioTTM) suggest good liquidity to meet short-term obligations, providing financial stability.
  • Positive Revenue Growth: Income Statements reflect consistent revenue growth over recent periods, supported by diversified product categories and geographic segments as per Revenue Product Segments and Revenue Geo Segments data. This indicates robust demand for CNTA’s offerings.
  • Strong Operating Cash Flow: Cash Flow Statements show positive net cash provided by operating activities and free cash flow (freeCashFlow), highlighting CNTA’s ability to generate cash from core operations, which supports reinvestment and debt management.
  • Industry Positioning: CNTA operates within a competitive industry (industryName) and sector (sectorName) with performance metrics (perf1w, perf1m, etc.) aligning with or exceeding industry averages (industry_perf1w, industry_perf1m), indicating a strong market position.

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At what price to buy it? -
Intrinsic Value Calculator

Based on current fundamentals and analyst forecasts, MarketSnap estimates CNTA intrinsic value between $2.22 – $4.88 per share. This depends on revenue growth, margins, and discount rate.

This is an automatic estimate. The most reliable way to know fair value for your own assumptions is to run the calculator below.


Calculate CNTA Intrinsic Value

Common questions about CNTA valuation

Is Centessa Pharmaceuticals plc (CNTA) overvalued or undervalued right now?

MarketSnap estimates intrinsic value for Centessa Pharmaceuticals plc (CNTA) using its proprietary valuation methodology, which incorporates discounted cash flow (DCF) analysis together with long-term earnings and fundamentals assumptions. By comparing intrinsic value to the current market price, long-term investors can see whether the stock screens as potentially overvalued, fairly valued, or undervalued today.

Is CNTA a buy, hold, or sell for long-term investors?

MarketSnap does not give one-word “buy” or “sell” calls. Instead, it shows whether CNTA trades at a premium or discount to its estimated intrinsic value, how sensitive that value is to growth and margin assumptions, and how the stock fits into a diversified, long-term portfolio so investors can make their own buy, hold, or sell decision.

What is CNTA’s P/E ratio?

You can see CNTA’s trailing P/E (TTM) and forward P/E estimates in the Current Key Metrics and Forward P/E Ratios sections above. The P/E ratio compares the current share price to earnings per share and helps investors gauge valuation relative to earnings.

How is intrinsic value calculated for CNTA?

MarketSnap uses its own valuation framework—not a generic spreadsheet DCF alone. Future cash flows and earnings are projected, discounted, and combined with MarketSnap’s methodology so intrinsic value reflects fundamentals and long-term assumptions. You can run your own inputs and see the result using the Intrinsic Value Calculator above.

Is CNTA a good long-term investment?

Whether CNTA fits a long-term portfolio depends on your assumptions about growth, margins, and risk. MarketSnap provides the metrics, intrinsic value calculator, and SWOT context so you can form your own view rather than rely on a single buy/sell rating.

Research tools for Centessa Pharmaceuticals plc

  • Centessa Pharmaceuticals plc intrinsic value calculatorEstimate what the business is worth
  • Centessa Pharmaceuticals plc 5-year outlookWhat has to go right, and what could go wrong
CNTA

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Daily snapshot

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Trading Metrics:

Open: 40.5   Previous Close: 40.5
Day Low: 40.5   Day High: 40.5
Year Low: 12.78   Year High: 40.56
Price Avg 50: 39.71   Price Avg 200: 29.33
Volume: 0   Average Volume: 2.94M

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Relevant news

Acquisition of Centessa by Lilly Approved by the High Court of Justice of England and Wales
22-06-2026 16:05
Acquisition of Centessa by Lilly Approved by the High Court of Justice of England and Wales

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