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AXSM stock logo

AXSM

Axsome Therapeutics, Inc.

$245.64
10.5
 (4.47%)
Exchange:  NASDAQ
Market Cap:  12.641B
Shares Outstanding:  12.718M
Delayed data
Calculate AXSM Intrinsic Value
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Overview
Earnings
Financials
Valuation
Chart

About The Company

Sector:  Healthcare
Industry:  Biotechnology
   
CEO:  Herriot Tabuteau
Full Time Employees:  712
Address: 
22 Cortlandt Street
New York City
NY
10007
US
Website:  https://www.axsome.com
Axsome Therapeutics, Inc. is a biopharmaceutical company dedicated to discovering and advancing innovative treatments for a range of central nervous system (CNS) disorders within the United States. Its robust product pipeline features several promising candidates, including: AXS-05, an investigational therapy currently being developed for major depressive disorder and treatment-resistant depression. This compound is also in Phase III clinical evaluation for Alzheimer’s disease agitation and has successfully finished Phase II trials investigating its use for smoking cessation. AXS-07, a novel, orally administered, rapidly-acting investigational medicine that employs multiple mechanisms of action. It has concluded two Phase III studies for the acute treatment of migraine attacks. AXS-12, a selective and potent norepinephrine reuptake inhibitor, which is presently undergoing a Phase III trial for narcolepsy. AXS-14, an oral investigational drug, advancing through Phase III trials for the management of fibromyalgia. Axsome Therapeutics also engages in a research collaboration with Duke University to further assess AXS-05’s potential in smoking cessation. The company, established in 2012, has its main offices in New York, New York.

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Revenue Segmentation

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EPS

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Earnings Call

Full text

Earnings transcript

Read the complete earnings call transcript.

AI summary

Key takeaways

Short, structured highlights from the call so you can focus on what matters.

2026/05/04 — Q1 quarter 2026

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Income Statement
Balance Sheet
Cash Flow Statement
Analyst Estimates

Income Statement

Year202320242025
Revenue270,600385,693638,496
Gross Profit244,535352,390591,018
EBITDA-224,991-272,604-168,083
Operating Income-231,825-280,562-169,235
Net Income-239,238-287,216-183,174

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(* All numbers are in thousands)

Balance Sheet

Year202320242025
Total Assets588,236568,498689,805
Total Liabilities397,259511,483601,510
Total Stockholders Equity190,97757,01588,295
Total Debt186,372192,955215,568
Cash and Cash Equivalents386,193315,353322,933

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Cash Flow Statement

Year202320242025
Operating Cash Flow-145,080-128,410-93,405
Capital Expenditure-582-2700
Free Cash Flow-145,662-128,680-93,405
Net Income-239,238-287,216-183,174
Net Change in Cash185,351-70,8407,580

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(* All numbers are in thousands)

Analyst Estimates

Fiscal Year2030Full AccessFull AccessFull AccessFull Access
Estimated Revenue (Low)3,138,920.218Full AccessFull AccessFull AccessFull Access
Estimated Revenue (High)4,447,965.294Full AccessFull AccessFull AccessFull Access
Estimated Revenue (Avg)3,755,163.060Full AccessFull AccessFull AccessFull Access
Estimated Ebitda (Low)-1,602,593.679Full AccessFull AccessFull AccessFull Access
Estimated Ebitda (High)-1,130,947.156Full AccessFull AccessFull AccessFull Access
Estimated Ebitda (Avg)-1,352,978.314Full AccessFull AccessFull AccessFull Access
Estimated Net Income (Low)1,236,915.848Full AccessFull AccessFull AccessFull Access
Estimated Net Income (High)1,949,474.541Full AccessFull AccessFull AccessFull Access
Estimated Net Income (Avg)1,572,358.091Full AccessFull AccessFull AccessFull Access
Estimated SGA Expense (Low)4,606,069.908Full AccessFull AccessFull AccessFull Access
Estimated SGA Expense (High)6,526,970.318Full AccessFull AccessFull AccessFull Access
Estimated SGA Expense (Avg)5,510,348.263Full AccessFull AccessFull AccessFull Access
Estimated EPS (Avg)31.610Full AccessFull AccessFull AccessFull Access
Estimated EPS (High)39.190Full AccessFull AccessFull AccessFull Access
Estimated EPS (Low)24.860Full AccessFull AccessFull AccessFull Access
Number of Analysts (Estimated Revenue)8Full AccessFull AccessFull AccessFull Access
Number of Analysts (Estimated EPS)14Full AccessFull AccessFull AccessFull Access

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(* All numbers are in thousands)

Current Key Metrics

?Revenue
 (TTM)
: 
385.693M  ?P/S
 (TTM)
: 
16.88
?Net Income
 (TTM)
: 
-287216000  ?P/E
 (TTM)
: 
-63.17
?Enterprise Value
 (TTM)
: 
11.867B  ?EV/FCF
 (TTM)
: 
-167.15
?Dividend Yield
 (TTM)
: 
0  ?Payout Ratio
 (TTM)
: 
0
?ROE
 (TTM)
: 
-2.6  ?ROIC
 (TTM)
: 
-0.51
?Net Debt
 (TTM)
: 
-112440000  ?Debt/Equity
 (TTM)
: 
3.97
?P/B
 (TTM)
: 
217.9  ?Current Ratio
 (TTM)
: 
1.39

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Forward P/E Ratios

?

Forward P/E (Avg EPS estimate) — log in with Full Access for high/low estimates and the interactive table.

Forward P/E 1YFull AccessFull AccessFull AccessFull Access
N/AFull AccessFull AccessFull AccessFull Access

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SWOT Analysis

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At what price to buy it? -
Intrinsic Value Calculator

This is an automatic estimate. The most reliable way to know fair value for your own assumptions is to run the calculator below.

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Common questions about AXSM valuation

Is Axsome Therapeutics, Inc. (AXSM) overvalued or undervalued right now?

MARKETSnap estimates intrinsic value for Axsome Therapeutics, Inc. (AXSM) using its proprietary valuation methodology, which incorporates discounted cash flow (DCF) analysis together with long-term earnings and fundamentals assumptions. By comparing intrinsic value to the current market price, long-term investors can see whether the stock screens as potentially overvalued, fairly valued, or undervalued today.

Is AXSM a buy, hold, or sell for long-term investors?

MARKETSnap does not give one-word “buy” or “sell” calls. Instead, it shows whether AXSM trades at a premium or discount to its estimated intrinsic value, how sensitive that value is to growth and margin assumptions, and how the stock fits into a diversified, long-term portfolio so investors can make their own buy, hold, or sell decision.

What is AXSM’s P/E ratio?

You can see AXSM’s trailing P/E (TTM) and forward P/E estimates in the Current Key Metrics and Forward P/E Ratios sections above. The P/E ratio compares the current share price to earnings per share and helps investors gauge valuation relative to earnings.

How is intrinsic value calculated for AXSM?

MARKETSnap uses its own valuation framework—not a generic spreadsheet DCF alone. Future cash flows and earnings are projected, discounted, and combined with MARKETSnap’s methodology so intrinsic value reflects fundamentals and long-term assumptions. You can run your own inputs and see the result using the Intrinsic Value Calculator above.

Is AXSM a good long-term investment?

Whether AXSM fits a long-term portfolio depends on your assumptions about growth, margins, and risk. MARKETSnap provides the metrics, intrinsic value calculator, and SWOT context so you can form your own view rather than rely on a single buy/sell rating.

AXSM

1-day price chart preview. Log in for 1W through 5Y ranges and period tabs.

Daily snapshot

4.47
MARKETSnap

Trading Metrics:

Open: 237.21   Previous Close: 235.14
Day Low: 236.38   Day High: 246.41
Year Low: 96.09   Year High: 246.41
Price Avg 50: 204.6   Price Avg 200: 162.89
Volume: 870329   Average Volume: 701007

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See in Nexus

Relevant news

Axsome Therapeutics, Inc. (AXSM) Presents at Goldman Sachs 47th Annual Global Healthcare Conference 2026 Transcript
08-06-2026 17:58
Axsome Therapeutics, Inc. (AXSM) Presents at Goldman Sachs 47th Annual Global Healthcare Conference 2026 Transcript
Axsome Therapeutics Bets on AUVELITY Expansion With June Alzheimer's Agitation Launch
12-05-2026 18:08
Axsome Therapeutics Bets on AUVELITY Expansion With June Alzheimer's Agitation Launch
Axsome Therapeutics, Inc. (AXSM) Presents at Bank of America Global Healthcare Conference 2026 Transcript
12-05-2026 14:20
Axsome Therapeutics, Inc. (AXSM) Presents at Bank of America Global Healthcare Conference 2026 Transcript
AXSM Q1 Loss Widens, Revenues Jump on Higher Auvelity Sales
05-05-2026 13:50
AXSM Q1 Loss Widens, Revenues Jump on Higher Auvelity Sales
Axsome Therapeutics Q1 2026 Earnings Review: Gains Mystify Me, But Can't Be Denied
04-05-2026 12:32
Axsome Therapeutics Q1 2026 Earnings Review: Gains Mystify Me, But Can't Be Denied
Axsome Therapeutics (AXSM) Reports Q1 Loss, Beats Revenue Estimates
04-05-2026 09:15
Axsome Therapeutics (AXSM) Reports Q1 Loss, Beats Revenue Estimates

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