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APLS stock logo

APLS

Apellis Pharmaceuticals, Inc.

$40.41
0.02
 (0.05%)
[ms_data_label text=’Delayed data’]
Exchange:  NASDAQ
Market Cap:  5.166B
Shares Outstanding:  18.093M
Overview
Earnings
Financials
Valuation
Chart

About The Company

Sector:  Healthcare
Industry:  Biotechnology
   
CEO:  Cedric Francois
Full Time Employees:  705
Address: 
100 Fifth Avenue
Waltham
MA
2451
US
Website:  https://www.apellis.com
Apellis Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, focuses on the discovery, development, and commercialization of therapeutic compounds through the inhibition of the complement system for autoimmune and inflammatory diseases. The company’s lead product candidate is pegcetacoplan that is in Phase III clinical trials for the treatment of geographic atrophy (GA) in age-related macular degeneration and paroxysmal nocturnal hemoglobinuria (PNH) diseases. It also develops EMPAVELI (systemic pegcetacoplan) for the treatment of cold agglutinin disease (CAD), and hematopoietic stem cell transplantation-associated thrombotic microangiopathy (HSCT-TMA) in hematology; C3 glomerulopathy (C3G), and immune complex membranoproliferative glomerulonephritis (IC-MPGN) in nephrology; and amyotrophic lateral sclerosis (ALS) in neurology. In addition, the company develops APL-2006, a bispecific C3 and VEGF inhibitor for treating complement-mediated disorders; APL-1030, a C3 inhibitor for the treatment of multiple neurodegenerative diseases; and the combination of EMPAVELI and a small interfering RNA, or siRNA for reducing the production of C3 proteins by the liver. It has a collaboration and license agreement with Swedish Orphan Biovitrum AB (publ) to co-develop pegcetacoplan; and a research collaboration with Beam Therapeutics Inc. focused on the use of Beam’s base editing technology to discover new treatments for complement-driven diseases. Apellis Pharmaceuticals, Inc. was incorporated in 2009 and is based in Waltham, Massachusetts.

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Revenue Segmentation

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EPS

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Earnings Call

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Earnings transcript

Read the complete earnings call transcript.

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2025/05/07 — Q1 quarter 2025

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Income Statement
Balance Sheet
Cash Flow Statement
Analyst Estimates

Income Statement

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(* All numbers are in thousands)

Balance Sheet

Year202320242025
Total Assets788,730885,0511,075,257
Total Liabilities594,209656,512705,110
Total Stockholders Equity194,521228,539370,147
Total Debt110,928469,784112,696
Cash and Cash Equivalents351,185411,290466,233

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Cash Flow Statement

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Analyst Estimates

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(* All numbers are in thousands)

Current Key Metrics

?Revenue
 (TTM)
: 
781.367M  ?P/S
 (TTM)
: 
5.22
?Net Income
 (TTM)
: 
-197878000  ?P/E
 (TTM)
: 
230.57
?Enterprise Value
 (TTM)
: 
5.262B  ?EV/FCF
 (TTM)
: 
116.1
?Dividend Yield
 (TTM)
: 
0  ?Payout Ratio
 (TTM)
: 
0
?ROE
 (TTM)
: 
0.08  ?ROIC
 (TTM)
: 
0.06
?Net Debt
 (TTM)
: 
57.172M  ?Debt/Equity
 (TTM)
: 
1.31
?P/B
 (TTM)
: 
13.95  ?Current Ratio
 (TTM)
: 
3.14

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Forward P/E Ratios

?

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SWOT Analysis

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Intrinsic Value Calculator

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Common questions about APLS valuation

Is Apellis Pharmaceuticals, Inc. (APLS) overvalued or undervalued right now?

MARKETSnap estimates intrinsic value for Apellis Pharmaceuticals, Inc. (APLS) using its proprietary valuation methodology, which incorporates discounted cash flow (DCF) analysis together with long-term earnings and fundamentals assumptions. By comparing intrinsic value to the current market price, long-term investors can see whether the stock screens as potentially overvalued, fairly valued, or undervalued today.

Is APLS a buy, hold, or sell for long-term investors?

MARKETSnap does not give one-word “buy” or “sell” calls. Instead, it shows whether APLS trades at a premium or discount to its estimated intrinsic value, how sensitive that value is to growth and margin assumptions, and how the stock fits into a diversified, long-term portfolio so investors can make their own buy, hold, or sell decision.

What is APLS’s P/E ratio?

You can see APLS’s trailing P/E (TTM) and forward P/E estimates in the Current Key Metrics and Forward P/E Ratios sections above. The P/E ratio compares the current share price to earnings per share and helps investors gauge valuation relative to earnings.

How is intrinsic value calculated for APLS?

MARKETSnap uses its own valuation framework—not a generic spreadsheet DCF alone. Future cash flows and earnings are projected, discounted, and combined with MARKETSnap’s methodology so intrinsic value reflects fundamentals and long-term assumptions. You can run your own inputs and see the result using the Intrinsic Value Calculator above.

Is APLS a good long-term investment?

Whether APLS fits a long-term portfolio depends on your assumptions about growth, margins, and risk. MARKETSnap provides the metrics, intrinsic value calculator, and SWOT context so you can form your own view rather than rely on a single buy/sell rating.

APLS

1-day price chart preview. Log in for 1W through 5Y ranges and period tabs.

[ms_data_label text="Daily snapshot"]

0.05
MARKETSnap

Trading Metrics:

[ms_session_rows_unavailable]
Open: [ms_cell_or_dash table='trading_quote' column='open']   Previous Close: [ms_cell_or_dash table='trading_quote' column='previousClose']
Day Low: [ms_cell_or_dash table='trading_quote' column='dayLow']   Day High: [ms_cell_or_dash table='trading_quote' column='dayHigh']
Year Low: 16.1   Year High: 40.48
Price Avg 50: 21.88   Price Avg 200: 22.75
Volume: 10.333M   Average Volume: 4.866M

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Relevant news

Apellis Pharmaceuticals, Inc. (NASDAQ:APLS) Given Average Rating of “Hold” by Analysts
10-04-2026 03:18
Apellis Pharmaceuticals, Inc. (NASDAQ:APLS) Given Average Rating of “Hold” by Analysts
SHAREHOLDER ALERT: The M&A Class Action Firm Announces An Investigation of Apellis Pharmaceuticals, Inc. (NASDAQ: APLS)
01-04-2026 16:07
SHAREHOLDER ALERT: The M&A Class Action Firm Announces An Investigation of Apellis Pharmaceuticals, Inc. (NASDAQ: APLS)
Apellis Pharmaceuticals (APLS) Moves 135.4% Higher: Will This Strength Last?
01-04-2026 08:55
Apellis Pharmaceuticals (APLS) Moves 135.4% Higher: Will This Strength Last?
Why This Pharma Stock More Than Doubled Today
31-03-2026 09:41
Why This Pharma Stock More Than Doubled Today
Why Is Apellis Pharmaceuticals (APLS) Down 17.3% Since Last Earnings Report?
26-03-2026 12:32
Why Is Apellis Pharmaceuticals (APLS) Down 17.3% Since Last Earnings Report?
Apellis Pharmaceuticals, Inc. (APLS) Presents at TD Cowen 46th Annual Health Care Conference Transcript
02-03-2026 12:57
Apellis Pharmaceuticals, Inc. (APLS) Presents at TD Cowen 46th Annual Health Care Conference Transcript

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