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GPCR stock logo

GPCR

Structure Therapeutics Inc.

$53.48
3.31
 (6.6%)
[ms_data_label text=’Delayed data’]
Exchange:  NASDAQ
Market Cap:  3.079B
Shares Outstanding:  36.588M
Overview
Earnings
Financials
Valuation
Chart

About The Company

Sector:  Healthcare
Industry:  Biotechnology
   
CEO:  Raymond C. Stevens
Full Time Employees:  163
Address: 
611 Gateway Boulevard
South San Francisco
CA
94080
US
Website:  https://structuretx.com
Structure Therapeutics Inc., a clinical stage global biopharmaceutical company, develops and delivers novel oral therapeutics to treat a range of chronic diseases with unmet medical needs. Its lead product candidate is GSBR-1290, an oral and biased small molecule agonist of glucagon-like-peptide-1 receptor, a validated G-protein-coupled receptors (GPCRs) drug target for type-2 diabetes mellitus and obesity. The company is also developing oral small molecule therapeutics targeting other GPCRs for the treatment of pulmonary and cardiovascular diseases, including ANPA-0073, a biased agonist, targeting apelin receptor, a GPCR that has been implicated in idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension; and LTSE-2578, an investigational oral small molecule lysophosphatidic acid 1 receptor antagonist for the treatment of IPF. The company was formerly known as ShouTi Inc. Structure Therapeutics Inc. was founded in 2016 and is headquartered in South San Francisco, California.

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Revenue Segmentation

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EPS

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Earnings Call

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Income Statement
Balance Sheet
Cash Flow Statement
Analyst Estimates

Income Statement

Year202320242025
Revenue000
Gross Profit00-3,899.285
EBITDA-102,480-157,236-136,787.715
Operating Income-102,775-158,228-287,567.533
Net Income-89,620-122,526-141,202

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(* All numbers are in thousands)

Balance Sheet

Year202320242025
Total Assets482,017903,3301,583,918
Total Liabilities29,05138,48767,541
Total Stockholders Equity452,966864,8431,516,377
Total Debt5,4533,8626,487
Cash and Cash Equivalents129,792169,510799,623

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Cash Flow Statement

Year202320242025
Operating Cash Flow-79,418.903-116,636-222,199
Capital Expenditure-2,165.116-1,290-3,614
Free Cash Flow-81,584.019-117,926-225,813
Net Income-89,542.096-122,526-141,202
Net Change in Cash103,700.97239,7180

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(* All numbers are in thousands)

Analyst Estimates

Fiscal Year2030Full AccessFull AccessFull AccessFull Access
Estimated Revenue (Low)817,653Full AccessFull AccessFull AccessFull Access
Estimated Revenue (High)817,653Full AccessFull AccessFull AccessFull Access
Estimated Revenue (Avg)817,653Full AccessFull AccessFull AccessFull Access
Estimated Ebitda (Low)0Full AccessFull AccessFull AccessFull Access
Estimated Ebitda (High)0Full AccessFull AccessFull AccessFull Access
Estimated Ebitda (Avg)0Full AccessFull AccessFull AccessFull Access
Estimated Net Income (Low)77,465.600Full AccessFull AccessFull AccessFull Access
Estimated Net Income (High)77,465.600Full AccessFull AccessFull AccessFull Access
Estimated Net Income (Avg)77,465.600Full AccessFull AccessFull AccessFull Access
Estimated SGA Expense (Low)0Full AccessFull AccessFull AccessFull Access
Estimated SGA Expense (High)0Full AccessFull AccessFull AccessFull Access
Estimated SGA Expense (Avg)0Full AccessFull AccessFull AccessFull Access
Estimated EPS (Avg)1.310Full AccessFull AccessFull AccessFull Access
Estimated EPS (High)1.310Full AccessFull AccessFull AccessFull Access
Estimated EPS (Low)1.310Full AccessFull AccessFull AccessFull Access
Number of Analysts (Estimated Revenue)5Full AccessFull AccessFull AccessFull Access
Number of Analysts (Estimated EPS)6Full AccessFull AccessFull AccessFull Access

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(* All numbers are in thousands)

Current Key Metrics

?Revenue
 (TTM)
: 
0  ?P/S
 (TTM)
: 
0
?Net Income
 (TTM)
: 
-122587456.4  ?P/E
 (TTM)
: 
-17.7
?Enterprise Value
 (TTM)
: 
1.637B  ?EV/FCF
 (TTM)
: 
-7.25
?Dividend Yield
 (TTM)
: 
0  ?Payout Ratio
 (TTM)
: 
0
?ROE
 (TTM)
: 
-0.15  ?ROIC
 (TTM)
: 
-0.12
?Net Debt
 (TTM)
: 
-879653580.9  ?Debt/Equity
 (TTM)
: 
0
?P/B
 (TTM)
: 
1.65  ?Current Ratio
 (TTM)
: 
24.81

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Forward P/E Ratios

?

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Forward P/E 1YFull AccessFull AccessFull AccessFull Access
N/AFull AccessFull AccessFull AccessFull Access

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SWOT Analysis

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At what price to buy it? -
Intrinsic Value Calculator

This is an automatic estimate. The most reliable way to know fair value for your own assumptions is to run the calculator below.


Calculate GPCR Intrinsic Value

Common questions about GPCR valuation

Is Structure Therapeutics Inc. (GPCR) overvalued or undervalued right now?

MARKETSnap estimates intrinsic value for Structure Therapeutics Inc. (GPCR) using its proprietary valuation methodology, which incorporates discounted cash flow (DCF) analysis together with long-term earnings and fundamentals assumptions. By comparing intrinsic value to the current market price, long-term investors can see whether the stock screens as potentially overvalued, fairly valued, or undervalued today.

Is GPCR a buy, hold, or sell for long-term investors?

MARKETSnap does not give one-word “buy” or “sell” calls. Instead, it shows whether GPCR trades at a premium or discount to its estimated intrinsic value, how sensitive that value is to growth and margin assumptions, and how the stock fits into a diversified, long-term portfolio so investors can make their own buy, hold, or sell decision.

What is GPCR’s P/E ratio?

You can see GPCR’s trailing P/E (TTM) and forward P/E estimates in the Current Key Metrics and Forward P/E Ratios sections above. The P/E ratio compares the current share price to earnings per share and helps investors gauge valuation relative to earnings.

How is intrinsic value calculated for GPCR?

MARKETSnap uses its own valuation framework—not a generic spreadsheet DCF alone. Future cash flows and earnings are projected, discounted, and combined with MARKETSnap’s methodology so intrinsic value reflects fundamentals and long-term assumptions. You can run your own inputs and see the result using the Intrinsic Value Calculator above.

Is GPCR a good long-term investment?

Whether GPCR fits a long-term portfolio depends on your assumptions about growth, margins, and risk. MARKETSnap provides the metrics, intrinsic value calculator, and SWOT context so you can form your own view rather than rely on a single buy/sell rating.

GPCR

1-day price chart preview. Log in for 1W through 5Y ranges and period tabs.

[ms_data_label text="Daily snapshot"]

6.6
MARKETSnap

Trading Metrics:

[ms_session_rows_unavailable]
Open: [ms_cell_or_dash table='trading_quote' column='open']   Previous Close: [ms_cell_or_dash table='trading_quote' column='previousClose']
Day Low: [ms_cell_or_dash table='trading_quote' column='dayLow']   Day High: [ms_cell_or_dash table='trading_quote' column='dayHigh']
Year Low: 13.22   Year High: 94.9
Price Avg 50: 65.85   Price Avg 200: 41.8
Volume: 1.708M   Average Volume: 959331

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See in Nexus

Relevant news

Structure Therapeutics Inc. (GPCR) Discusses Positive Topline Results from ACCESS II and Related Studies of Aleniglipron Oral GLP-1 Transcript
16-03-2026 12:32
Structure Therapeutics Inc. (GPCR) Discusses Positive Topline Results from ACCESS II and Related Studies of Aleniglipron Oral GLP-1 Transcript
Structure Therapeutics Stock Explodes As Much-Awaited Experimental Oral Drug Trial Shows Weight Loss Of 16%
16-03-2026 09:27
Structure Therapeutics Stock Explodes As Much-Awaited Experimental Oral Drug Trial Shows Weight Loss Of 16%
Why Weight-Loss Contender Structure Therapeutics Just Shot Skyward
16-03-2026 09:13
Why Weight-Loss Contender Structure Therapeutics Just Shot Skyward
Structure Therapeutics: The Dark Horse Has Taken The Lead - But Is It Enough?
18-02-2026 16:51
Structure Therapeutics: The Dark Horse Has Taken The Lead - But Is It Enough?
Nxera Pharma Licenses GPCR-targeted Program to Newly Founded Spin-out Company
12-02-2026 03:38
Nxera Pharma Licenses GPCR-targeted Program to Newly Founded Spin-out Company
Osaic Holdings Inc. Buys 31,972 Shares of Structure Therapeutics Inc. Sponsored ADR $GPCR
01-01-2026 05:32
Osaic Holdings Inc. Buys 31,972 Shares of Structure Therapeutics Inc. Sponsored ADR $GPCR

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