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WVE stock logo

WVE

Wave Life Sciences Ltd.

$5.78
0.08
 (1.4%)
Exchange:  NASDAQ
Market Cap:  1.112B
Shares Outstanding:  20.933M
Delayed data
Calculate WVE Intrinsic Value
5-year outlook →
Overview
Earnings
Financials
Valuation
Chart

About The Company

Sector:  Healthcare
Industry:  Biotechnology
   
CEO:  Paul Bolno
Full Time Employees:  287
Address: 
Marina One East Tower
Singapore
18936
SG
Website:  https://www.wavelifesciences.com
Wave Life Sciences Ltd. (WVE) is a clinical-stage genetic medicine firm dedicated to inventing, refining, and manufacturing novel stereopure oligonucleotide therapies. The company utilizes its proprietary PRISM platform for discovery and drug development. These specialized oligonucleotides are designed to interact with ribonucleic acid (RNA) to precisely modulate protein expression within the body. This involves either diminishing the production of disease-causing proteins, restoring the synthesis of functional proteins, or generally adjusting protein levels as needed. The company’s pipeline includes several key programs targeting neurological disorders. WVE-004, a C9orf72 molecule, is being developed for amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). WVE-003 focuses on the mutant huntingtin SNP3 molecule for Huntington’s disease, while WVE-N531 targets Exon 53 for Duchenne muscular dystrophy. Additionally, ATXN3 is an early-stage program addressing spinocerebellar ataxia 3, complemented by multiple other preclinical initiatives for central nervous system (CNS) conditions. Beyond CNS applications, Wave Life Sciences is also developing GalNAc-conjugated AIMers for various hepatic indications, including Alpha-1 antitrypsin deficiency (AATD). Their preclinical efforts extend to ocular diseases, with programs for Usher syndrome type 2A (USH2A) and retinitis pigmentosa caused by a P23H mutation in the RHO gene (RhoP23H). Wave Life Sciences actively collaborates with a diverse array of partners, such as pharmaceutical companies like Pfizer Inc. and Takeda Pharmaceutical Company Limited, alongside academic and research institutions including the University of Oxford, University of Massachusetts, Western Washington University, Grenoble Institute of Neurosciences, IRBM S.p.A., University of Louisville, and University College London. Established in 2012, the company is headquartered in Singapore.

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Revenue Segmentation

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EPS

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Earnings Call

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Earnings transcript

Read the complete earnings call transcript.

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Key takeaways

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2026/04/28 — Q1 quarter 2026

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Income Statement
Balance Sheet
Cash Flow Statement
Analyst Estimates

Income Statement

Year202320242025
Revenue113,305108,30242,727
Gross Profit113,305108,30233,875
EBITDA-58,790-101,740-195,526
Operating Income-67,996-110,403-215,383
Net Income-57,513-97,008-204,378

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(* All numbers are in thousands)

Balance Sheet

Year202320242025
Total Assets274,949352,20723,685
Total Liabilities235,319142,69217,203
Total Stockholders Equity39,630209,515518,357
Total Debt32,11825,40417,766
Cash and Cash Equivalents200,351302,078602,068

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Cash Flow Statement

Year202320242025
Operating Cash Flow-19,431-151,026-187,493
Capital Expenditure-1,11500
Free Cash Flow-20,546-151,026-187,493
Net Income-57,5130-204,378
Net Change in Cash111,893101,788300,036

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(* All numbers are in thousands)

Analyst Estimates

Fiscal Year2030Full AccessFull AccessFull AccessFull Access
Estimated Revenue (Low)234,782.875Full AccessFull AccessFull AccessFull Access
Estimated Revenue (High)791,245.687Full AccessFull AccessFull AccessFull Access
Estimated Revenue (Avg)499,235.558Full AccessFull AccessFull AccessFull Access
Estimated Ebitda (Low)-705,518.201Full AccessFull AccessFull AccessFull Access
Estimated Ebitda (High)-209,345.332Full AccessFull AccessFull AccessFull Access
Estimated Ebitda (Avg)-445,145.899Full AccessFull AccessFull AccessFull Access
Estimated Net Income (Low)16,738.365Full AccessFull AccessFull AccessFull Access
Estimated Net Income (High)94,632.773Full AccessFull AccessFull AccessFull Access
Estimated Net Income (Avg)53,757.122Full AccessFull AccessFull AccessFull Access
Estimated SGA Expense (Low)832,503.603Full AccessFull AccessFull AccessFull Access
Estimated SGA Expense (High)2,805,634.292Full AccessFull AccessFull AccessFull Access
Estimated SGA Expense (Avg)1,770,211.736Full AccessFull AccessFull AccessFull Access
Estimated EPS (Avg)0.320Full AccessFull AccessFull AccessFull Access
Estimated EPS (High)0.560Full AccessFull AccessFull AccessFull Access
Estimated EPS (Low)0.100Full AccessFull AccessFull AccessFull Access
Number of Analysts (Estimated Revenue)6Full AccessFull AccessFull AccessFull Access
Number of Analysts (Estimated EPS)4Full AccessFull AccessFull AccessFull Access

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(* All numbers are in thousands)

Current Key Metrics

?Revenue
 (TTM)
: 
108.302M  ?P/S
 (TTM)
: 
15.36
?Net Income
 (TTM)
: 
-97008000  ?P/E
 (TTM)
: 
-6.25
?Enterprise Value
 (TTM)
: 
573.589M  ?EV/FCF
 (TTM)
: 
-3.13
?Dividend Yield
 (TTM)
: 
0  ?Payout Ratio
 (TTM)
: 
0
?ROE
 (TTM)
: 
-0.56  ?ROIC
 (TTM)
: 
-0.36
?Net Debt
 (TTM)
: 
-276674000  ?Debt/Equity
 (TTM)
: 
0.03
?P/B
 (TTM)
: 
2.24  ?Current Ratio
 (TTM)
: 
11.26

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Forward P/E Ratios

?

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Forward P/E 1YFull AccessFull AccessFull AccessFull Access
N/AFull AccessFull AccessFull AccessFull Access

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SWOT Analysis

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At what price to buy it? -
Intrinsic Value Calculator

This is an automatic estimate. The most reliable way to know fair value for your own assumptions is to run the calculator below.

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Common questions about WVE valuation

Is Wave Life Sciences Ltd. (WVE) overvalued or undervalued right now?

MARKETSnap estimates intrinsic value for Wave Life Sciences Ltd. (WVE) using its proprietary valuation methodology, which incorporates discounted cash flow (DCF) analysis together with long-term earnings and fundamentals assumptions. By comparing intrinsic value to the current market price, long-term investors can see whether the stock screens as potentially overvalued, fairly valued, or undervalued today.

Is WVE a buy, hold, or sell for long-term investors?

MARKETSnap does not give one-word “buy” or “sell” calls. Instead, it shows whether WVE trades at a premium or discount to its estimated intrinsic value, how sensitive that value is to growth and margin assumptions, and how the stock fits into a diversified, long-term portfolio so investors can make their own buy, hold, or sell decision.

What is WVE’s P/E ratio?

You can see WVE’s trailing P/E (TTM) and forward P/E estimates in the Current Key Metrics and Forward P/E Ratios sections above. The P/E ratio compares the current share price to earnings per share and helps investors gauge valuation relative to earnings.

How is intrinsic value calculated for WVE?

MARKETSnap uses its own valuation framework—not a generic spreadsheet DCF alone. Future cash flows and earnings are projected, discounted, and combined with MARKETSnap’s methodology so intrinsic value reflects fundamentals and long-term assumptions. You can run your own inputs and see the result using the Intrinsic Value Calculator above.

Is WVE a good long-term investment?

Whether WVE fits a long-term portfolio depends on your assumptions about growth, margins, and risk. MARKETSnap provides the metrics, intrinsic value calculator, and SWOT context so you can form your own view rather than rely on a single buy/sell rating.

WVE

1-day price chart preview. Log in for 1W through 5Y ranges and period tabs.

Daily snapshot

1.4
MARKETSnap

Trading Metrics:

Open: 5.75   Previous Close: 5.7
Day Low: 5.68   Day High: 6
Year Low: 5.02   Year High: 21.73
Price Avg 50: 6.86   Price Avg 200: 9.95
Volume: 3.769M   Average Volume: 4.763M

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See in Nexus

Relevant news

Wave Life Sciences: 'Strong Buy' On DMD NDA Filing WVE-N531 And Released AATD Data
20-05-2026 13:21
Wave Life Sciences: 'Strong Buy' On DMD NDA Filing WVE-N531 And Released AATD Data
Wave Life Sciences Supports AlphaDetect to Accelerate Detection of Alpha-1
19-05-2026 09:49
Wave Life Sciences Supports AlphaDetect to Accelerate Detection of Alpha-1
Wave Life Sciences Announces Positive Update on RestorAATion-2 Trial: WVE-006 (GalNAc-RNA Editing) Achieves MZ-Like Phenotype Across Both Biweekly and Monthly Dosing
18-05-2026 16:30
Wave Life Sciences Announces Positive Update on RestorAATion-2 Trial: WVE-006 (GalNAc-RNA Editing) Achieves MZ-Like Phenotype Across Both Biweekly and Monthly Dosing
Wave Life Sciences (WVE) Reports Q1 Loss, Beats Revenue Estimates
28-04-2026 09:46
Wave Life Sciences (WVE) Reports Q1 Loss, Beats Revenue Estimates
Is This Weight Loss Drug Stock a Buy on the Dip?
01-04-2026 16:45
Is This Weight Loss Drug Stock a Buy on the Dip?
Wave Life Sciences (WVE) Surges 9.5%: Is This an Indication of Further Gains?
01-04-2026 04:21
Wave Life Sciences (WVE) Surges 9.5%: Is This an Indication of Further Gains?

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