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SNDX stock logo

SNDX

Syndax Pharmaceuticals, Inc.

$12.9
-0.75
 (-5.49%)
Exchange:  NASDAQ
Market Cap:  1.152B
Shares Outstanding:  70.284M
Delayed data
Overview
Earnings
Financials
Valuation
Chart

About The Company

Sector:  HealthcareView sector performance
Industry:  BiotechnologyView industry performance
   
CEO:  Michael A. Metzger
Full Time Employees:  298
Address: 
730 Third Avenue
New York City
NY
10017
US
Website:  https://www.syndax.com
Syndax Pharmaceuticals, Inc. operates as a clinical-stage biopharmaceutical firm focused on developing innovative therapies for cancer. Among its leading investigational products are SNDX-5613, currently undergoing Phase 1/2 clinical assessment, which targets the Menin-mixed lineage leukemia 1 protein interaction for treating MLL-rearranged (MLLr) and nucleophosmin 1 mutant acute myeloid leukemia (NPM1c AML). Another significant candidate is SNDX-6352, or axatilimab, a monoclonal antibody designed to block the colony stimulating factor 1 (CSF-1) receptor, intended for patients suffering from chronic graft versus host disease (cGVHD). The company is additionally progressing Entinostat. Syndax has also established strategic collaborations, including a research and development agreement with the National Cancer Institute, a clinical trial agreement with the Eastern Cooperative Oncology Group, and a license agreement with Kyowa Hakko Kirin Co., Ltd. Founded in 2005, Syndax Pharmaceuticals, Inc. maintains its corporate headquarters in Waltham, Massachusetts.

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Revenue Segmentation

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Industry Peers

TICKERCOMPANYMKT CAPP/EFWD P/EROIC
SNSNDX logoSNDXSyndax Pharmaceuticals, Inc.1.2B——-32.1%
KAKARD logoKARDKardigan, Inc.1.2B——-20.4%
DMDMRA logoDMRADamora Therapeutics, Inc.1.1B——-52.4%
DRDRTS logoDRTSAlpha Tau Medical Ltd1.1B——-40.0%
OMOMER logoOMEROmeros Corporation1.2B10.417.8-31.1%
TSTSHA logoTSHATaysha Gene Therapies, Inc.1.2B——-34.5%

EPS

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View full analyst estimates

Earnings Call

Full text

Earnings transcript

Read the complete earnings call transcript.

AI summary

Key takeaways

Short, structured highlights from the call so you can focus on what matters.

2026/08/03 — Q2 quarter 2026

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Income Statement
Balance Sheet
Cash Flow Statement
Analyst Estimates

Income Statement

Year202320242025
Revenue023,680172,352
Gross Profit022,854165,382
EBITDA-209,140-313,821-251,631
Operating Income-229,954-339,672-273,084
Net Income-209,360-318,758-285,422

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(* All numbers are in thousands)

Balance Sheet

Year202320242025
Total Assets612,880724,816529,706
Total Liabilities58,684436,692344,960
Total Stockholders Equity554,196288,12464,630
Total Debt1,635345,7390
Cash and Cash Equivalents295,394154,083134,930

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(* All numbers are in thousands)

Cash Flow Statement

Year202320242025
Operating Cash Flow-160,601-274,903-322,980
Capital Expenditure00-187
Free Cash Flow-160,601-274,903-323,167
Net Income-209,360-318,758-285,422
Net Change in Cash221,140-141,311-19,268

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(* All numbers are in thousands)

Analyst Estimates

Fiscal Year2030Research AccessResearch AccessResearch AccessResearch Access
Estimated Revenue (Low)938,629.897Research AccessResearch AccessResearch AccessResearch Access
Estimated Revenue (High)1,283,597.533Research AccessResearch AccessResearch AccessResearch Access
Estimated Revenue (Avg)1,067,031.285Research AccessResearch AccessResearch AccessResearch Access
Estimated Ebitda (Low)271,979.530Research AccessResearch AccessResearch AccessResearch Access
Estimated Ebitda (High)400,921.203Research AccessResearch AccessResearch AccessResearch Access
Estimated Ebitda (Avg)319,973.408Research AccessResearch AccessResearch AccessResearch Access
Estimated Net Income (Low)204,452.034Research AccessResearch AccessResearch AccessResearch Access
Estimated Net Income (High)306,315.956Research AccessResearch AccessResearch AccessResearch Access
Estimated Net Income (Avg)242,367.198Research AccessResearch AccessResearch AccessResearch Access
Estimated SGA Expense (Low)1,563,360.392Research AccessResearch AccessResearch AccessResearch Access
Estimated SGA Expense (High)2,137,930.562Research AccessResearch AccessResearch AccessResearch Access
Estimated SGA Expense (Avg)1,777,222.794Research AccessResearch AccessResearch AccessResearch Access
Estimated EPS (Avg)2.800Research AccessResearch AccessResearch AccessResearch Access
Estimated EPS (High)3.540Research AccessResearch AccessResearch AccessResearch Access
Estimated EPS (Low)2.360Research AccessResearch AccessResearch AccessResearch Access
Number of Analysts (Estimated Revenue)5Research AccessResearch AccessResearch AccessResearch Access
Number of Analysts (Estimated EPS)5Research AccessResearch AccessResearch AccessResearch Access

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(* All numbers are in thousands)

Current Key Metrics

?Revenue
 (TTM)
: 
23.68M  ?P/S
 (TTM)
: 
5.97
?Net Income
 (TTM)
: 
-318.758M  ?P/E
 (TTM)
: 
-6.74
?Enterprise Value
 (TTM)
: 
1.758B  ?EV/FCF
 (TTM)
: 
-7.96
?Dividend Yield
 (TTM)
: 
0%  ?Payout Ratio
 (TTM)
: 
0%
?ROE
 (TTM)
: 
-372.94%  ?ROIC
 (TTM)
: 
-32.1%
?Net Debt
 (TTM)
: 
-227.145M  ?Debt/Equity
 (TTM)
: 
39.03
?P/B
 (TTM)
: 
100.14  ?Current Ratio
 (TTM)
: 
6.77

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Forward P/E Ratios

?

Forward P/E (Avg EPS estimate) — log in with Research Access for high/low estimates and the interactive table.

Forward P/E 1YResearch AccessResearch AccessResearch AccessResearch Access
N/AResearch AccessResearch AccessResearch AccessResearch Access

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SWOT Analysis

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At what price to buy it? -
Intrinsic Value Calculator

Based on current fundamentals and analyst forecasts, MarketSnap estimates SNDX intrinsic value between $31.27 – $48.92 per share. This depends on revenue growth, margins, and discount rate.

This is an automatic estimate. The most reliable way to know fair value for your own assumptions is to run the calculator below.


Calculate SNDX Intrinsic Value

Common questions about SNDX valuation

Is Syndax Pharmaceuticals, Inc. (SNDX) overvalued or undervalued right now?

MarketSnap estimates intrinsic value for Syndax Pharmaceuticals, Inc. (SNDX) using its proprietary valuation methodology, which incorporates discounted cash flow (DCF) analysis together with long-term earnings and fundamentals assumptions. By comparing intrinsic value to the current market price, long-term investors can see whether the stock screens as potentially overvalued, fairly valued, or undervalued today.

Is SNDX a buy, hold, or sell for long-term investors?

MarketSnap does not give one-word “buy” or “sell” calls. Instead, it shows whether SNDX trades at a premium or discount to its estimated intrinsic value, how sensitive that value is to growth and margin assumptions, and how the stock fits into a diversified, long-term portfolio so investors can make their own buy, hold, or sell decision.

What is SNDX’s P/E ratio?

You can see SNDX’s trailing P/E (TTM) and forward P/E estimates in the Current Key Metrics and Forward P/E Ratios sections above. The P/E ratio compares the current share price to earnings per share and helps investors gauge valuation relative to earnings.

How is intrinsic value calculated for SNDX?

MarketSnap uses its own valuation framework—not a generic spreadsheet DCF alone. Future cash flows and earnings are projected, discounted, and combined with MarketSnap’s methodology so intrinsic value reflects fundamentals and long-term assumptions. You can run your own inputs and see the result using the Intrinsic Value Calculator above.

Is SNDX a good long-term investment?

Whether SNDX fits a long-term portfolio depends on your assumptions about growth, margins, and risk. MarketSnap provides the metrics, intrinsic value calculator, and SWOT context so you can form your own view rather than rely on a single buy/sell rating.

Research tools for Syndax Pharmaceuticals, Inc.

  • Syndax Pharmaceuticals, Inc. intrinsic value calculatorEstimate what the business is worth
  • Syndax Pharmaceuticals, Inc. 5-year outlookWhat has to go right, and what could go wrong
SNDX

1-day price chart preview. Log in for 1W through 5Y ranges and period tabs.

Daily snapshot

-5.49
MarketSnap

Trading Metrics:

Open: 13.55   Previous Close: 13.65
Day Low: 12.82   Day High: 13.61
Year Low: 12.82   Year High: 25.59
Price Avg 50: 18.61   Price Avg 200: 20.65
Volume: 2.833M   Average Volume: 1.805M

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See in Nexus

Relevant news

Syndax Investigation Notice: SueWallSt Notifies Investors of Pending Investigation Into Syndax (SNDX)
13-10-2026 22:17
Syndax Investigation Notice: SueWallSt Notifies Investors of Pending Investigation Into Syndax (SNDX)
Syndax Announces Topline Results from MAXPIRe Phase 2 Trial of Axatilimab in Idiopathic Pulmonary Fibrosis
12-10-2026 16:01
Syndax Announces Topline Results from MAXPIRe Phase 2 Trial of Axatilimab in Idiopathic Pulmonary Fibrosis
Syndax Pharmaceuticals Reports Inducement Grants Under NASDAQ Listing Rule 5635(c)(4)
01-07-2026 16:01
Syndax Pharmaceuticals Reports Inducement Grants Under NASDAQ Listing Rule 5635(c)(4)
Syndax: 'Strong Buy' Revuforj Pipeline Growth And Niktimvo Q4 2026 Data Releases
28-09-2026 05:22
Syndax: 'Strong Buy' Revuforj Pipeline Growth And Niktimvo Q4 2026 Data Releases
Syndax Pharmaceuticals: Buy The Pullback Ahead Of Q4 Readouts
25-09-2026 12:28
Syndax Pharmaceuticals: Buy The Pullback Ahead Of Q4 Readouts
Syndax Pharmaceuticals, Inc. (SNDX) Presents at Citigroup's Biopharma Back to School Summit 2026 Transcript
10-09-2026 16:57
Syndax Pharmaceuticals, Inc. (SNDX) Presents at Citigroup's Biopharma Back to School Summit 2026 Transcript

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