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RARE stock logo

RARE

Ultragenyx Pharmaceutical Inc.

$26.13
-0.32
 (-1.19%)
Exchange:  NASDAQ
Market Cap:  2.573B
Shares Outstanding:  23.063M
Delayed data
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Overview
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About The Company

Sector:  Healthcare
Industry:  Biotechnology
   
CEO:  Emil D. Kakkis
Full Time Employees:  1371
Address: 
60 Leveroni Court
Novato
CA
94949
US
Website:  https://www.ultragenyx.com
Ultragenyx Pharmaceutical Inc. is a biopharmaceutical firm dedicated to discovering, developing, and commercializing innovative treatments for rare and ultra-rare genetic conditions. Its operations span North America, Europe, and other international markets. The company’s portfolio of marketed biologic products addresses several serious diseases. This includes Crysvita (burosumab), an antibody that targets fibroblast growth factor 23, used to treat X-linked hypophosphatemia and tumor-induced osteomalacia. Mepsevii offers enzyme replacement therapy for both pediatric and adult patients suffering from Mucopolysaccharidosis VII. Dojolvi is available for individuals with long-chain fatty acid oxidation disorders, while Evkeeza (evinacumab) provides a treatment option for homozygous familial hypercholesterolemia. Ultragenyx also boasts a robust pipeline of investigational therapies. Notable candidates include DTX401, an adeno-associated virus 8 (AAV8) gene therapy for glycogen storage disease type Ia, and DTX301, another AAV8 gene therapy aimed at ornithine transcarbamylase deficiency. Other promising developments feature UX143, a human monoclonal antibody for osteogenesis imperfecta; GTX-102, an antisense oligonucleotide designed for Angelman syndrome; UX701, targeting Wilson disease; and UX053, in development for glycogen storage disease type III. To advance its research and development efforts, Ultragenyx Pharmaceutical Inc. maintains strategic collaboration and licensing agreements with numerous partners, such as Kyowa Kirin Co., Ltd., Saint Louis University, REGENXBIO Inc., Bayer Healthcare LLC, GeneTx, Mereo, University of Pennsylvania, Arcturus Therapeutics Holdings Inc., Solid Biosciences Inc., and Daiichi Sankyo Co., Ltd. The company was founded in 2010 and operates from its headquarters in Novato, California.

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Revenue Segmentation

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EPS

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Earnings Call

Full text

Earnings transcript

Read the complete earnings call transcript.

AI summary

Key takeaways

Short, structured highlights from the call so you can focus on what matters.

2026/05/06 — Q1 quarter 2026

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Income Statement
Balance Sheet
Cash Flow Statement
Analyst Estimates

Income Statement

Year202320242025
Revenue434,249560,230673,000
Gross Profit389,040483,502564,000
EBITDA-516,454-469,002-474,000
Operating Income-569,208-535,973-535,000
Net Income-606,639-569,183-575,000

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(* All numbers are in thousands)

Balance Sheet

Year202320242025
Total Assets1,491,0131,503,4561,532,000
Total Liabilities1,215,5991,241,1591,605,000
Total Stockholders Equity275,414255,29716,158.999
Total Debt43,169910,01012,000
Cash and Cash Equivalents213,584173,729421,000

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(* All numbers are in thousands)

Cash Flow Statement

Year202320242025
Operating Cash Flow-474,806-414,188-466,000
Capital Expenditure-46,767-7,491-6,000
Free Cash Flow-521,573-421,679-472,000
Net Income-606,639-569,183-575,000
Net Change in Cash81,798-35,240-184,159

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(* All numbers are in thousands)

Analyst Estimates

Fiscal Year2030Research AccessResearch AccessResearch AccessResearch Access
Estimated Revenue (Low)1,821,199.864Research AccessResearch AccessResearch AccessResearch Access
Estimated Revenue (High)2,947,352.227Research AccessResearch AccessResearch AccessResearch Access
Estimated Revenue (Avg)2,173,158.889Research AccessResearch AccessResearch AccessResearch Access
Estimated Ebitda (Low)-2,677,061.637Research AccessResearch AccessResearch AccessResearch Access
Estimated Ebitda (High)-1,654,184.472Research AccessResearch AccessResearch AccessResearch Access
Estimated Ebitda (Avg)-1,973,866.659Research AccessResearch AccessResearch AccessResearch Access
Estimated Net Income (Low)410,996.356Research AccessResearch AccessResearch AccessResearch Access
Estimated Net Income (High)761,716.559Research AccessResearch AccessResearch AccessResearch Access
Estimated Net Income (Avg)520,608.005Research AccessResearch AccessResearch AccessResearch Access
Estimated SGA Expense (Low)1,164,689.795Research AccessResearch AccessResearch AccessResearch Access
Estimated SGA Expense (High)1,884,884.317Research AccessResearch AccessResearch AccessResearch Access
Estimated SGA Expense (Avg)1,389,773.869Research AccessResearch AccessResearch AccessResearch Access
Estimated EPS (Avg)5.280Research AccessResearch AccessResearch AccessResearch Access
Estimated EPS (High)7.730Research AccessResearch AccessResearch AccessResearch Access
Estimated EPS (Low)4.170Research AccessResearch AccessResearch AccessResearch Access
Number of Analysts (Estimated Revenue)12Research AccessResearch AccessResearch AccessResearch Access
Number of Analysts (Estimated EPS)5Research AccessResearch AccessResearch AccessResearch Access

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(* All numbers are in thousands)

Current Key Metrics

?Revenue
 (TTM)
: 
560.23M  ?P/S
 (TTM)
: 
3.55
?Net Income
 (TTM)
: 
-569183000  ?P/E
 (TTM)
: 
-4.42
?Enterprise Value
 (TTM)
: 
3.621B  ?EV/FCF
 (TTM)
: 
-7.4
?Dividend Yield
 (TTM)
: 
0%  ?Payout Ratio
 (TTM)
: 
0%
?ROE
 (TTM)
: 
392.35%  ?ROIC
 (TTM)
: 
-53.48%
?Net Debt
 (TTM)
: 
293.179M  ?Debt/Equity
 (TTM)
: 
-4.13
?P/B
 (TTM)
: 
-9.04  ?Current Ratio
 (TTM)
: 
1.73

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Forward P/E Ratios

?

Forward P/E (Avg EPS estimate) — log in with Research Access for high/low estimates and the interactive table.

Forward P/E 1YResearch AccessResearch AccessResearch AccessResearch Access
N/AResearch AccessResearch AccessResearch AccessResearch Access

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SWOT Analysis

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At what price to buy it? -
Intrinsic Value Calculator

This is an automatic estimate. The most reliable way to know fair value for your own assumptions is to run the calculator below.

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Common questions about RARE valuation

Is Ultragenyx Pharmaceutical Inc. (RARE) overvalued or undervalued right now?

MARKETSnap estimates intrinsic value for Ultragenyx Pharmaceutical Inc. (RARE) using its proprietary valuation methodology, which incorporates discounted cash flow (DCF) analysis together with long-term earnings and fundamentals assumptions. By comparing intrinsic value to the current market price, long-term investors can see whether the stock screens as potentially overvalued, fairly valued, or undervalued today.

Is RARE a buy, hold, or sell for long-term investors?

MARKETSnap does not give one-word “buy” or “sell” calls. Instead, it shows whether RARE trades at a premium or discount to its estimated intrinsic value, how sensitive that value is to growth and margin assumptions, and how the stock fits into a diversified, long-term portfolio so investors can make their own buy, hold, or sell decision.

What is RARE’s P/E ratio?

You can see RARE’s trailing P/E (TTM) and forward P/E estimates in the Current Key Metrics and Forward P/E Ratios sections above. The P/E ratio compares the current share price to earnings per share and helps investors gauge valuation relative to earnings.

How is intrinsic value calculated for RARE?

MARKETSnap uses its own valuation framework—not a generic spreadsheet DCF alone. Future cash flows and earnings are projected, discounted, and combined with MARKETSnap’s methodology so intrinsic value reflects fundamentals and long-term assumptions. You can run your own inputs and see the result using the Intrinsic Value Calculator above.

Is RARE a good long-term investment?

Whether RARE fits a long-term portfolio depends on your assumptions about growth, margins, and risk. MARKETSnap provides the metrics, intrinsic value calculator, and SWOT context so you can form your own view rather than rely on a single buy/sell rating.

RARE

1-day price chart preview. Log in for 1W through 5Y ranges and period tabs.

Daily snapshot

-1.19
MARKETSnap

Trading Metrics:

Open: 26.38   Previous Close: 26.44
Day Low: 25.94   Day High: 26.54
Year Low: 18.29   Year High: 39.89
Price Avg 50: 28.43   Price Avg 200: 26.34
Volume: 382914   Average Volume: 2.119M

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See in Nexus

Relevant news

Ultragenyx's gene therapy for rare metabolic disorder secures US FDA nod
19-08-2026 17:33
Ultragenyx's gene therapy for rare metabolic disorder secures US FDA nod
Ultragenyx Announces U.S. FDA Approval of GENGLYCOS™ Gene Therapy, the First-Ever FDA-Approved Treatment Designed to Treat the Underlying Cause of Glycogen Storage Disease Type Ia (GSDIa)
19-08-2026 17:21
Ultragenyx Announces U.S. FDA Approval of GENGLYCOS™ Gene Therapy, the First-Ever FDA-Approved Treatment Designed to Treat the Underlying Cause of Glycogen Storage Disease Type Ia (GSDIa)
Ultragenyx: Undervalued Ahead Of Two FDA Decisions
14-08-2026 02:15
Ultragenyx: Undervalued Ahead Of Two FDA Decisions
Ultragenyx Pharmaceutical Inc. (RARE) Q2 2026 Earnings Call Transcript
05-08-2026 05:40
Ultragenyx Pharmaceutical Inc. (RARE) Q2 2026 Earnings Call Transcript
Ultragenyx Pharmaceutical Q2 Earnings Call Highlights
04-08-2026 22:05
Ultragenyx Pharmaceutical Q2 Earnings Call Highlights
Entropy Technologies LP Grows Position in Ultragenyx Pharmaceutical Inc. $RARE
27-07-2026 04:04
Entropy Technologies LP Grows Position in Ultragenyx Pharmaceutical Inc. $RARE

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