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PTGX stock logo

PTGX

Protagonist Therapeutics, Inc.

$150.56
-0.94
 (-0.62%)
Exchange:  NASDAQ
Market Cap:  9.683B
Shares Outstanding:  5.885M
Delayed data
Calculate PTGX Intrinsic Value
5-year outlook →
Overview
Earnings
Financials
Valuation
Chart

About The Company

Sector:  Healthcare
Industry:  Biotechnology
   
CEO:  Dinesh V. Patel
Full Time Employees:  141
Address: 
7707 Gateway Boulevard
Newark
CA
94560
US
Website:  https://www.protagonist-inc.com
Protagonist Therapeutics, Inc. is a biopharmaceutical firm dedicated to discovering and advancing peptide-based therapies. Their research primarily focuses on treatments for hematological and blood conditions, as well as inflammatory and immune-mediated disorders. The company’s pipeline features rusfertide (PTG-300), an injectable hepcidin mimetic currently undergoing Phase II clinical trials for the management of polycythemia vera, hereditary hemochromatosis, and other blood-related ailments. Also in Phase II development is PN-943, an oral peptide engineered as a specific antagonist of alpha-4-beta-7 integrin, intended for addressing inflammatory bowel disease (IBD). Furthermore, they are progressing PN-235, an orally administered antagonist specifically targeting the interleukin-23 receptor, designed for both IBD and various non-IBD therapeutic applications. Protagonist Therapeutics maintains a licensing and collaborative agreement with Janssen Biotech, Inc. Founded in 2006, the company’s headquarters are located in Newark, California.

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Revenue Segmentation

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EPS

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Earnings Call

Full text

Earnings transcript

Read the complete earnings call transcript.

AI summary

Key takeaways

Short, structured highlights from the call so you can focus on what matters.

2021/03/10 — 4 quarter 2020

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Income Statement
Balance Sheet
Cash Flow Statement
Analyst Estimates

Income Statement

Year202320242025
Revenue60,000434,43346,016
Gross Profit60,000434,43344,791
EBITDA-75,643280,234-128,086
Operating Income-93,652252,843-158,127
Net Income-78,955275,188-130,149

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(* All numbers are in thousands)

Balance Sheet

Year202320242025
Total Assets357,951744,725668,188
Total Liabilities21,27469,43053,481
Total Stockholders Equity336,677675,295614,707
Total Debt1,14110,86610,323
Cash and Cash Equivalents186,72797,249128,390

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(* All numbers are in thousands)

Cash Flow Statement

Year202320242025
Operating Cash Flow-70,236184,15257,671
Capital Expenditure-609-1,3550
Free Cash Flow-70,845182,79757,671
Net Income-78,955275,1880
Net Change in Cash60,983-89,4780

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(* All numbers are in thousands)

Analyst Estimates

Fiscal Year2030Research AccessResearch AccessResearch AccessResearch Access
Estimated Revenue (Low)557,236.785Research AccessResearch AccessResearch AccessResearch Access
Estimated Revenue (High)1,289,520.204Research AccessResearch AccessResearch AccessResearch Access
Estimated Revenue (Avg)832,606.500Research AccessResearch AccessResearch AccessResearch Access
Estimated Ebitda (Low)-865,253.384Research AccessResearch AccessResearch AccessResearch Access
Estimated Ebitda (High)-373,899.542Research AccessResearch AccessResearch AccessResearch Access
Estimated Ebitda (Avg)-558,669.488Research AccessResearch AccessResearch AccessResearch Access
Estimated Net Income (Low)271,918.459Research AccessResearch AccessResearch AccessResearch Access
Estimated Net Income (High)817,311.646Research AccessResearch AccessResearch AccessResearch Access
Estimated Net Income (Avg)477,009.565Research AccessResearch AccessResearch AccessResearch Access
Estimated SGA Expense (Low)425,853.255Research AccessResearch AccessResearch AccessResearch Access
Estimated SGA Expense (High)985,481.203Research AccessResearch AccessResearch AccessResearch Access
Estimated SGA Expense (Avg)636,297.169Research AccessResearch AccessResearch AccessResearch Access
Estimated EPS (Avg)7.500Research AccessResearch AccessResearch AccessResearch Access
Estimated EPS (High)12.860Research AccessResearch AccessResearch AccessResearch Access
Estimated EPS (Low)4.280Research AccessResearch AccessResearch AccessResearch Access
Number of Analysts (Estimated Revenue)4Research AccessResearch AccessResearch AccessResearch Access
Number of Analysts (Estimated EPS)4Research AccessResearch AccessResearch AccessResearch Access

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(* All numbers are in thousands)

Current Key Metrics

?Revenue
 (TTM)
: 
434.433M  ?P/S
 (TTM)
: 
35.19
?Net Income
 (TTM)
: 
275.188M  ?P/E
 (TTM)
: 
126.69
?Enterprise Value
 (TTM)
: 
9.514B  ?EV/FCF
 (TTM)
: 
71.98
?Dividend Yield
 (TTM)
: 
0%  ?Payout Ratio
 (TTM)
: 
0%
?ROE
 (TTM)
: 
12.03%  ?ROIC
 (TTM)
: 
6.74%
?Net Debt
 (TTM)
: 
-408047000  ?Debt/Equity
 (TTM)
: 
0.01
?P/B
 (TTM)
: 
12.09  ?Current Ratio
 (TTM)
: 
21.71

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Forward P/E Ratios

?

Forward P/E (Avg EPS estimate) — log in with Research Access for high/low estimates and the interactive table.

Forward P/E 1YResearch AccessResearch AccessResearch AccessResearch Access
33.02Research AccessResearch AccessResearch AccessResearch Access

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SWOT Analysis

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At what price to buy it? -
Intrinsic Value Calculator

Based on current fundamentals and analyst forecasts, MARKETSnap estimates PTGX intrinsic value between $18.77 – $41.33 per share. This depends on revenue growth, margins, and discount rate.

This is an automatic estimate. The most reliable way to know fair value for your own assumptions is to run the calculator below.

[intrinsic_calculator]

Common questions about PTGX valuation

Is Protagonist Therapeutics, Inc. (PTGX) overvalued or undervalued right now?

MARKETSnap estimates intrinsic value for Protagonist Therapeutics, Inc. (PTGX) using its proprietary valuation methodology, which incorporates discounted cash flow (DCF) analysis together with long-term earnings and fundamentals assumptions. By comparing intrinsic value to the current market price, long-term investors can see whether the stock screens as potentially overvalued, fairly valued, or undervalued today.

Is PTGX a buy, hold, or sell for long-term investors?

MARKETSnap does not give one-word “buy” or “sell” calls. Instead, it shows whether PTGX trades at a premium or discount to its estimated intrinsic value, how sensitive that value is to growth and margin assumptions, and how the stock fits into a diversified, long-term portfolio so investors can make their own buy, hold, or sell decision.

What is PTGX’s P/E ratio?

You can see PTGX’s trailing P/E (TTM) and forward P/E estimates in the Current Key Metrics and Forward P/E Ratios sections above. The P/E ratio compares the current share price to earnings per share and helps investors gauge valuation relative to earnings.

How is intrinsic value calculated for PTGX?

MARKETSnap uses its own valuation framework—not a generic spreadsheet DCF alone. Future cash flows and earnings are projected, discounted, and combined with MARKETSnap’s methodology so intrinsic value reflects fundamentals and long-term assumptions. You can run your own inputs and see the result using the Intrinsic Value Calculator above.

Is PTGX a good long-term investment?

Whether PTGX fits a long-term portfolio depends on your assumptions about growth, margins, and risk. MARKETSnap provides the metrics, intrinsic value calculator, and SWOT context so you can form your own view rather than rely on a single buy/sell rating.

PTGX

1-day price chart preview. Log in for 1W through 5Y ranges and period tabs.

Daily snapshot

-0.62
MARKETSnap

Trading Metrics:

Open: 150.35   Previous Close: 151.5
Day Low: 147.11   Day High: 151.68
Year Low: 54.5   Year High: 160.81
Price Avg 50: 136.7   Price Avg 200: 103.85
Volume: 166516   Average Volume: 657307

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See in Nexus

Relevant news

Surging Earnings Estimates Signal Upside for Protagonist Therapeutics (PTGX) Stock
07-08-2026 13:21
Surging Earnings Estimates Signal Upside for Protagonist Therapeutics (PTGX) Stock
Protagonist Therapeutics (PTGX) Beats Q2 Earnings Estimates
05-08-2026 18:26
Protagonist Therapeutics (PTGX) Beats Q2 Earnings Estimates
Protagonist Therapeutics Reports Granting of Inducement Awards
16-04-2026 16:05
Protagonist Therapeutics Reports Granting of Inducement Awards
Protagonist Exercises Rusfertide U.S. Opt-Out Right Under Takeda Collaboration
28-04-2026 09:05
Protagonist Exercises Rusfertide U.S. Opt-Out Right Under Takeda Collaboration

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