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PRME stock logo

PRME

Prime Medicine, Inc.

$3.62
0.04
 (0.98%)
Exchange:  NASDAQ
Market Cap:  652.932M
Shares Outstanding:  95.73M
Delayed data
Calculate PRME Intrinsic Value
5-year outlook →
Overview
Earnings
Financials
Valuation
Chart

About The Company

Sector:  Healthcare
Industry:  Biotechnology
   
CEO:  Allan Reine
Full Time Employees:  146
Address: 
60 First Street
Cambridge
MA
2141
US
Website:  https://www.primemedicine.com
Prime Medicine, Inc. operates as a biotechnology firm, dedicated to delivering genetic therapies for various diseases by strategically employing advanced gene editing technology. Central to their platform is the “Prime Editor” system, which combines a unique Prime Editor protein—a hybrid composed of a Cas protein and a reverse transcriptase enzyme—with a specialized pegRNA molecule. This pegRNA plays a crucial role by both guiding the Prime Editor to a precise location within the genome and providing the essential template for introducing the desired modification to the target DNA sequence. The company, founded in 2019, maintains its headquarters in Cambridge, Massachusetts.

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Revenue Segmentation

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EPS

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Earnings Call

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Income Statement
Balance Sheet
Cash Flow Statement
Analyst Estimates

Income Statement

Year202320242025
Revenue02,9834,632
Gross Profit02,983-2,689
EBITDA-186,639-189,754-195,758
Operating Income-204,792-202,467-208,350
Net Income-198,133-195,882-201,142

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(* All numbers are in thousands)

Balance Sheet

Year202320242025
Total Assets193,851297,508342,733
Total Liabilities60,780144,359221,865
Total Stockholders Equity133,071153,149120,868
Total Debt13,63340,794116,427
Cash and Cash Equivalents41,574182,47663,032

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(* All numbers are in thousands)

Cash Flow Statement

Year202320242025
Operating Cash Flow-165,412-122,865-162,564
Capital Expenditure-8,724-7,294-4,531
Free Cash Flow-174,136-130,159-167,095
Net Income-198,133-195,882-201,142
Net Change in Cash-146,046141,468-119,815

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(* All numbers are in thousands)

Analyst Estimates

Fiscal Year2030Research AccessResearch AccessResearch AccessResearch Access
Estimated Revenue (Low)8,224.657Research AccessResearch AccessResearch AccessResearch Access
Estimated Revenue (High)176,688.620Research AccessResearch AccessResearch AccessResearch Access
Estimated Revenue (Avg)48,025.600Research AccessResearch AccessResearch AccessResearch Access
Estimated Ebitda (Low)1,644.931Research AccessResearch AccessResearch AccessResearch Access
Estimated Ebitda (High)35,337.723Research AccessResearch AccessResearch AccessResearch Access
Estimated Ebitda (Avg)9,605.119Research AccessResearch AccessResearch AccessResearch Access
Estimated Net Income (Low)-564,601.092Research AccessResearch AccessResearch AccessResearch Access
Estimated Net Income (High)9,744.402Research AccessResearch AccessResearch AccessResearch Access
Estimated Net Income (Avg)-125,949.382Research AccessResearch AccessResearch AccessResearch Access
Estimated SGA Expense (Low)51,184.625Research AccessResearch AccessResearch AccessResearch Access
Estimated SGA Expense (High)1,099,588.825Research AccessResearch AccessResearch AccessResearch Access
Estimated SGA Expense (Avg)298,878.405Research AccessResearch AccessResearch AccessResearch Access
Estimated EPS (Avg)-0.850Research AccessResearch AccessResearch AccessResearch Access
Estimated EPS (High)0.070Research AccessResearch AccessResearch AccessResearch Access
Estimated EPS (Low)-3.800Research AccessResearch AccessResearch AccessResearch Access
Number of Analysts (Estimated Revenue)6Research AccessResearch AccessResearch AccessResearch Access
Number of Analysts (Estimated EPS)3Research AccessResearch AccessResearch AccessResearch Access

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(* All numbers are in thousands)

Current Key Metrics

?Revenue
 (TTM)
: 
2.983M  ?P/S
 (TTM)
: 
150.33
?Net Income
 (TTM)
: 
-195882000  ?P/E
 (TTM)
: 
-3.08
?Enterprise Value
 (TTM)
: 
677.32M  ?EV/FCF
 (TTM)
: 
-4.32
?Dividend Yield
 (TTM)
: 
0%  ?Payout Ratio
 (TTM)
: 
0%
?ROE
 (TTM)
: 
-188.27%  ?ROIC
 (TTM)
: 
-86.83%
?Net Debt
 (TTM)
: 
-149648000  ?Debt/Equity
 (TTM)
: 
2.83
?P/B
 (TTM)
: 
15.09  ?Current Ratio
 (TTM)
: 
3.05

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Forward P/E Ratios

?

Forward P/E (Avg EPS estimate) — log in with Research Access for high/low estimates and the interactive table.

Forward P/E 1YResearch AccessResearch AccessResearch AccessResearch Access
N/AResearch AccessResearch AccessResearch AccessResearch Access

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SWOT Analysis

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At what price to buy it? -
Intrinsic Value Calculator

This is an automatic estimate. The most reliable way to know fair value for your own assumptions is to run the calculator below.

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Common questions about PRME valuation

Is Prime Medicine, Inc. (PRME) overvalued or undervalued right now?

MARKETSnap estimates intrinsic value for Prime Medicine, Inc. (PRME) using its proprietary valuation methodology, which incorporates discounted cash flow (DCF) analysis together with long-term earnings and fundamentals assumptions. By comparing intrinsic value to the current market price, long-term investors can see whether the stock screens as potentially overvalued, fairly valued, or undervalued today.

Is PRME a buy, hold, or sell for long-term investors?

MARKETSnap does not give one-word “buy” or “sell” calls. Instead, it shows whether PRME trades at a premium or discount to its estimated intrinsic value, how sensitive that value is to growth and margin assumptions, and how the stock fits into a diversified, long-term portfolio so investors can make their own buy, hold, or sell decision.

What is PRME’s P/E ratio?

You can see PRME’s trailing P/E (TTM) and forward P/E estimates in the Current Key Metrics and Forward P/E Ratios sections above. The P/E ratio compares the current share price to earnings per share and helps investors gauge valuation relative to earnings.

How is intrinsic value calculated for PRME?

MARKETSnap uses its own valuation framework—not a generic spreadsheet DCF alone. Future cash flows and earnings are projected, discounted, and combined with MARKETSnap’s methodology so intrinsic value reflects fundamentals and long-term assumptions. You can run your own inputs and see the result using the Intrinsic Value Calculator above.

Is PRME a good long-term investment?

Whether PRME fits a long-term portfolio depends on your assumptions about growth, margins, and risk. MARKETSnap provides the metrics, intrinsic value calculator, and SWOT context so you can form your own view rather than rely on a single buy/sell rating.

PRME

1-day price chart preview. Log in for 1W through 5Y ranges and period tabs.

Daily snapshot

0.98
MARKETSnap

Trading Metrics:

Open: 3.55   Previous Close: 3.58
Day Low: 3.48   Day High: 3.67
Year Low: 2.67   Year High: 6.94
Price Avg 50: 3.32   Price Avg 200: 3.54
Volume: 1.363M   Average Volume: 3.009M

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See in Nexus

Relevant news

Prime Medicine, Inc. $PRME Shares Sold by Amova Asset Management Americas Inc.
21-07-2026 03:16
Prime Medicine, Inc. $PRME Shares Sold by Amova Asset Management Americas Inc.
Prime Medicine Beats Beam Therapeutics In Patent Dispute - But Both Are Investable
09-07-2026 10:22
Prime Medicine Beats Beam Therapeutics In Patent Dispute - But Both Are Investable
Prime Drink Group Announces Private Placement and Agreed Resolution with Creditors
12-06-2026 18:30
Prime Drink Group Announces Private Placement and Agreed Resolution with Creditors
Prime Medicine, Inc. (PRME) Presents at Jefferies Global Healthcare Conference 2026 Transcript
05-06-2026 16:12
Prime Medicine, Inc. (PRME) Presents at Jefferies Global Healthcare Conference 2026 Transcript
Prime Drink Group Announces Convertible Debenture, Board Appointment and Grant of Differed Share Units
14-04-2026 20:28
Prime Drink Group Announces Convertible Debenture, Board Appointment and Grant of Differed Share Units

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