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GYRE stock logo

GYRE

Gyre Therapeutics, Inc.

$6.68
0.03
 (0.45%)
Exchange:  NASDAQ
Market Cap:  744.746M
Shares Outstanding:  2603
Delayed data
Calculate GYRE Intrinsic Value
5-year outlook →
Overview
Earnings
Financials
Valuation
Chart

About The Company

Sector:  Healthcare
Industry:  Biotechnology
   
CEO:  Ying Luo
Full Time Employees:  625
Address: 
12770 High Bluff Drive
San Diego
CA
92130
US
Website:  https://www.gyretx.com
Gyre Therapeutics, Inc. is a pharmaceutical company dedicated to discovering, advancing, and bringing to market small-molecule drugs that target inflammation and fibrosis in various organs. The company’s key anti-fibrotic medication, ETUARY (Pirfenidone), has received approval for treating idiopathic pulmonary fibrosis. Beyond this, ETUARY is also undergoing late-stage (Phase 3) clinical trials for several other conditions, including dermatomyositis and interstitial lung disease linked to systemic sclerosis, pneumoconiosis, and diabetic kidney disease. The company’s pipeline further includes F351 (Hydronidone), a compound structurally related to ETUARY. F351 is currently in Phase 3 studies for chronic hepatitis B-induced liver fibrosis and is in Phase 1 trials for liver fibrosis associated with nonalcoholic associated steatohepatitis (NASH). Other programs in development feature F573, which is progressing through Phase 2 studies for acute and acute-on-chronic liver failure. Additionally, two early-stage candidates, F528 and F230, are in preclinical development, focusing on chronic obstructive pulmonary disease (COPD) and pulmonary arterial hypertension (PAH), respectively. Established in 2002, Gyre Therapeutics, Inc. is based in San Diego, California, and operates as a subsidiary of GNI USA, Inc.

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Revenue Segmentation

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EPS

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Earnings Call

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Income Statement
Balance Sheet
Cash Flow Statement
Analyst Estimates

Income Statement

Year202320242025
Revenue113,450105,757116,588
Gross Profit108,814101,873111,172
EBITDA20,32717,81716,956
Operating Income-67,23016,22911,491
Net Income-92,93312,0855,027

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(* All numbers are in thousands)

Balance Sheet

Year202320242025
Total Assets116,539125,406166,132
Total Liabilities38,06527,00423,850
Total Stockholders Equity-15,82863,319106,031
Total Debt4091,598939
Cash and Cash Equivalents33,50911,81337,070

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(* All numbers are in thousands)

Cash Flow Statement

Year202320242025
Operating Cash Flow25,892-3,6411,010
Capital Expenditure-8,586-2,315-1,190
Free Cash Flow17,306-5,956-180
Net Income-85,48017,8989,880
Net Change in Cash8,334-21,69625,257

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(* All numbers are in thousands)

Analyst Estimates

Fiscal Year2030Research AccessResearch AccessResearch AccessResearch Access
Estimated Revenue (Low)298,321.454Research AccessResearch AccessResearch AccessResearch Access
Estimated Revenue (High)319,825.448Research AccessResearch AccessResearch AccessResearch Access
Estimated Revenue (Avg)309,100Research AccessResearch AccessResearch AccessResearch Access
Estimated Ebitda (Low)-25,833.713Research AccessResearch AccessResearch AccessResearch Access
Estimated Ebitda (High)-24,096.741Research AccessResearch AccessResearch AccessResearch Access
Estimated Ebitda (Avg)-24,967.372Research AccessResearch AccessResearch AccessResearch Access
Estimated Net Income (Low)46,295.851Research AccessResearch AccessResearch AccessResearch Access
Estimated Net Income (High)50,682.034Research AccessResearch AccessResearch AccessResearch Access
Estimated Net Income (Avg)48,494.617Research AccessResearch AccessResearch AccessResearch Access
Estimated SGA Expense (Low)320,201.531Research AccessResearch AccessResearch AccessResearch Access
Estimated SGA Expense (High)343,282.714Research AccessResearch AccessResearch AccessResearch Access
Estimated SGA Expense (Avg)331,770.619Research AccessResearch AccessResearch AccessResearch Access
Estimated EPS (Avg)0.470Research AccessResearch AccessResearch AccessResearch Access
Estimated EPS (High)0.490Research AccessResearch AccessResearch AccessResearch Access
Estimated EPS (Low)0.450Research AccessResearch AccessResearch AccessResearch Access
Number of Analysts (Estimated Revenue)1Research AccessResearch AccessResearch AccessResearch Access
Number of Analysts (Estimated EPS)1Research AccessResearch AccessResearch AccessResearch Access

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(* All numbers are in thousands)

Current Key Metrics

?Revenue
 (TTM)
: 
105.757M  ?P/S
 (TTM)
: 
6.45
?Net Income
 (TTM)
: 
12.085M  ?P/E
 (TTM)
: 
-34.74
?Enterprise Value
 (TTM)
: 
730.519M  ?EV/FCF
 (TTM)
: 
-43.51
?Dividend Yield
 (TTM)
: 
0%  ?Payout Ratio
 (TTM)
: 
0%
?ROE
 (TTM)
: 
-15.77%  ?ROIC
 (TTM)
: 
-9.7%
?Net Debt
 (TTM)
: 
-25073000  ?Debt/Equity
 (TTM)
: 
0.03
?P/B
 (TTM)
: 
5.33  ?Current Ratio
 (TTM)
: 
4.26

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Forward P/E Ratios

?

Forward P/E (Avg EPS estimate) — log in with Research Access for high/low estimates and the interactive table.

Forward P/E 1YResearch AccessResearch AccessResearch AccessResearch Access
N/AResearch AccessResearch AccessResearch AccessResearch Access

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SWOT Analysis

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At what price to buy it? -
Intrinsic Value Calculator

This is an automatic estimate. The most reliable way to know fair value for your own assumptions is to run the calculator below.

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Common questions about GYRE valuation

Is Gyre Therapeutics, Inc. (GYRE) overvalued or undervalued right now?

MARKETSnap estimates intrinsic value for Gyre Therapeutics, Inc. (GYRE) using its proprietary valuation methodology, which incorporates discounted cash flow (DCF) analysis together with long-term earnings and fundamentals assumptions. By comparing intrinsic value to the current market price, long-term investors can see whether the stock screens as potentially overvalued, fairly valued, or undervalued today.

Is GYRE a buy, hold, or sell for long-term investors?

MARKETSnap does not give one-word “buy” or “sell” calls. Instead, it shows whether GYRE trades at a premium or discount to its estimated intrinsic value, how sensitive that value is to growth and margin assumptions, and how the stock fits into a diversified, long-term portfolio so investors can make their own buy, hold, or sell decision.

What is GYRE’s P/E ratio?

You can see GYRE’s trailing P/E (TTM) and forward P/E estimates in the Current Key Metrics and Forward P/E Ratios sections above. The P/E ratio compares the current share price to earnings per share and helps investors gauge valuation relative to earnings.

How is intrinsic value calculated for GYRE?

MARKETSnap uses its own valuation framework—not a generic spreadsheet DCF alone. Future cash flows and earnings are projected, discounted, and combined with MARKETSnap’s methodology so intrinsic value reflects fundamentals and long-term assumptions. You can run your own inputs and see the result using the Intrinsic Value Calculator above.

Is GYRE a good long-term investment?

Whether GYRE fits a long-term portfolio depends on your assumptions about growth, margins, and risk. MARKETSnap provides the metrics, intrinsic value calculator, and SWOT context so you can form your own view rather than rely on a single buy/sell rating.

GYRE

1-day price chart preview. Log in for 1W through 5Y ranges and period tabs.

Daily snapshot

0.45
MARKETSnap

Trading Metrics:

Open: 6.63   Previous Close: 6.65
Day Low: 6.63   Day High: 6.72
Year Low: 5.44   Year High: 9.42
Price Avg 50: 6.42   Price Avg 200: 7.19
Volume: 8189   Average Volume: 82178

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See in Nexus

Relevant news

Gyre Therapeutics, Inc. (GYRE) Reports Q2 Loss, Beats Revenue Estimates
07-08-2026 09:20
Gyre Therapeutics, Inc. (GYRE) Reports Q2 Loss, Beats Revenue Estimates
Kaskela Law LLC Announces Investigation of Gyre Therapeutics, Inc. (GYRE) and Encourages Long-Term GYRE Shareholders to Contact the Firm
27-05-2026 20:01
Kaskela Law LLC Announces Investigation of Gyre Therapeutics, Inc. (GYRE) and Encourages Long-Term GYRE Shareholders to Contact the Firm
Gyre Therapeutics Reports First Quarter 2026 Results and Provides Business Update
07-05-2026 06:00
Gyre Therapeutics Reports First Quarter 2026 Results and Provides Business Update
Gyre Therapeutics Completes Acquisition of Cullgen to Create U.S.- and China-based Fully Integrated Biopharmaceutical Company
04-05-2026 08:47
Gyre Therapeutics Completes Acquisition of Cullgen to Create U.S.- and China-based Fully Integrated Biopharmaceutical Company

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