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ARWR stock logo

ARWR

Arrowhead Pharmaceuticals, Inc.

$70.75
-2.58
 (-3.51%)
Exchange:  NASDAQ
Market Cap:  9.966B
Shares Outstanding:  4874
Delayed data
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Overview
Earnings
Financials
Valuation
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About The Company

Sector:  Healthcare
Industry:  Biotechnology
   
CEO:  Christopher R. Anzalone
Full Time Employees:  609
Address: 
177 East Colorado Boulevard
Pasadena
CA
91105
US
Website:  https://arrowheadpharma.com
Arrowhead Pharmaceuticals, Inc., founded in 1989 and based in Pasadena, California, is a biopharmaceutical company dedicated to discovering and advancing innovative treatments for complex and challenging-to-treat diseases within the United States. The company’s extensive therapeutic pipeline primarily leverages RNA interference (RNAi) technology. Among its advanced clinical programs are: ARO-AAT, a Phase II therapeutic targeting liver diseases associated with alpha-1 antitrypsin deficiency; ARO-APOC3, which is undergoing both Phase 2b and Phase 3 clinical evaluations for hypertriglyceridemia; ARO-ANG3, currently in Phase 2b development to reduce the production of angiopoietin-like protein 3; and ARO-HIF2, a Phase 1b candidate designed to treat clear cell renal cell carcinoma. Arrowhead also has several compounds in earlier clinical development, including ARO-HSD in Phase 1/2a for other liver diseases, ARO-ENaC in Phase 1/2a, aimed at decreasing the epithelial sodium channel alpha subunit in lung airways, and ARO-C3, also in Phase 1/2a, for complement-mediated diseases. Further expanding its diverse portfolio, the company is actively developing ARO-Lung2 for chronic obstructive pulmonary disorder (COPD), ARO-DUX4 for facioscapulohumeral muscular dystrophy, ARO-XDH for uncontrolled gout, and ARO-COV for COVID-19 and other pulmonary-borne pathogens. Beyond its core internal programs, Arrowhead is involved in the progression of JNJ-3989, a subcutaneously administered RNAi therapeutic for chronic hepatitis B virus infection; Olpasiran, intended to reduce apolipoprotein A production; and ARO-AMG1, which targets genetically validated cardiovascular pathways. Strategic collaborations are integral to Arrowhead’s development efforts. The company holds a licensing and research agreement with Janssen Pharmaceuticals, Inc. for the co-development of ARO-JNJ1, ARO-JNJ2, and ARO-JNJ3, all RNAi therapeutics focused on liver-expressed targets. Additionally, Arrowhead has a licensing and research partnership with Takeda Pharmaceuticals U.S.A., Inc. to develop an RNAi therapeutic candidate specifically for liver disease.

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Revenue Segmentation

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EPS

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Earnings Call

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Earnings transcript

Read the complete earnings call transcript.

AI summary

Key takeaways

Short, structured highlights from the call so you can focus on what matters.

2026/02/05 — Q1 quarter 2026

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Income Statement
Balance Sheet
Cash Flow Statement
Analyst Estimates

Income Statement

Year202320242025
Revenue240,7353,551829,448
Gross Profit228,242-15,044829,448
EBITDA-175,672-561,513164,822
Operating Income-205,002-601,08098,346
Net Income-205,275-599,493-1,631

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(* All numbers are in thousands)

Balance Sheet

Year202320242025
Total Assets765,5521,139,8021,385,295
Total Liabilities478,390948,739686,392
Total Stockholders Equity271,343185,444466,052
Total Debt383,497510,552111,401
Cash and Cash Equivalents110,891102,68588,706

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Cash Flow Statement

Year202320242025
Operating Cash Flow-153,890-462,851179,552
Capital Expenditure-176,737-141,469-22,666
Free Cash Flow-330,627-604,320156,886
Net Income-209,275-609,69330,114
Net Change in Cash2,886-8,206124,264

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(* All numbers are in thousands)

Analyst Estimates

Fiscal Year2030Full AccessFull AccessFull AccessFull Access
Estimated Revenue (Low)1,000,570.651Full AccessFull AccessFull AccessFull Access
Estimated Revenue (High)2,348,189.471Full AccessFull AccessFull AccessFull Access
Estimated Revenue (Avg)1,592,766.667Full AccessFull AccessFull AccessFull Access
Estimated Ebitda (Low)-1,482,628.089Full AccessFull AccessFull AccessFull Access
Estimated Ebitda (High)-631,752.322Full AccessFull AccessFull AccessFull Access
Estimated Ebitda (Avg)-1,005,660.160Full AccessFull AccessFull AccessFull Access
Estimated Net Income (Low)170,466.546Full AccessFull AccessFull AccessFull Access
Estimated Net Income (High)533,376.079Full AccessFull AccessFull AccessFull Access
Estimated Net Income (Avg)329,943.536Full AccessFull AccessFull AccessFull Access
Estimated SGA Expense (Low)5,780,785.972Full AccessFull AccessFull AccessFull Access
Estimated SGA Expense (High)13,566,638.939Full AccessFull AccessFull AccessFull Access
Estimated SGA Expense (Avg)9,202,191.966Full AccessFull AccessFull AccessFull Access
Estimated EPS (Avg)2.470Full AccessFull AccessFull AccessFull Access
Estimated EPS (High)3.990Full AccessFull AccessFull AccessFull Access
Estimated EPS (Low)1.270Full AccessFull AccessFull AccessFull Access
Number of Analysts (Estimated Revenue)5Full AccessFull AccessFull AccessFull Access
Number of Analysts (Estimated EPS)7Full AccessFull AccessFull AccessFull Access

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(* All numbers are in thousands)

Current Key Metrics

?Revenue
 (TTM)
: 
3.551M  ?P/S
 (TTM)
: 
16.55
?Net Income
 (TTM)
: 
-599493000  ?P/E
 (TTM)
: 
-34.59
?Enterprise Value
 (TTM)
: 
11.48B  ?EV/FCF
 (TTM)
: 
-225.66
?Dividend Yield
 (TTM)
: 
0  ?Payout Ratio
 (TTM)
: 
0
?ROE
 (TTM)
: 
-0.55  ?ROIC
 (TTM)
: 
-0.11
?Net Debt
 (TTM)
: 
319.111M  ?Debt/Equity
 (TTM)
: 
2.24
?P/B
 (TTM)
: 
16.95  ?Current Ratio
 (TTM)
: 
6.23

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Forward P/E Ratios

?

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Forward P/E 1YFull AccessFull AccessFull AccessFull Access
N/AFull AccessFull AccessFull AccessFull Access

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SWOT Analysis

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At what price to buy it? -
Intrinsic Value Calculator

This is an automatic estimate. The most reliable way to know fair value for your own assumptions is to run the calculator below.

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Common questions about ARWR valuation

Is Arrowhead Pharmaceuticals, Inc. (ARWR) overvalued or undervalued right now?

MARKETSnap estimates intrinsic value for Arrowhead Pharmaceuticals, Inc. (ARWR) using its proprietary valuation methodology, which incorporates discounted cash flow (DCF) analysis together with long-term earnings and fundamentals assumptions. By comparing intrinsic value to the current market price, long-term investors can see whether the stock screens as potentially overvalued, fairly valued, or undervalued today.

Is ARWR a buy, hold, or sell for long-term investors?

MARKETSnap does not give one-word “buy” or “sell” calls. Instead, it shows whether ARWR trades at a premium or discount to its estimated intrinsic value, how sensitive that value is to growth and margin assumptions, and how the stock fits into a diversified, long-term portfolio so investors can make their own buy, hold, or sell decision.

What is ARWR’s P/E ratio?

You can see ARWR’s trailing P/E (TTM) and forward P/E estimates in the Current Key Metrics and Forward P/E Ratios sections above. The P/E ratio compares the current share price to earnings per share and helps investors gauge valuation relative to earnings.

How is intrinsic value calculated for ARWR?

MARKETSnap uses its own valuation framework—not a generic spreadsheet DCF alone. Future cash flows and earnings are projected, discounted, and combined with MARKETSnap’s methodology so intrinsic value reflects fundamentals and long-term assumptions. You can run your own inputs and see the result using the Intrinsic Value Calculator above.

Is ARWR a good long-term investment?

Whether ARWR fits a long-term portfolio depends on your assumptions about growth, margins, and risk. MARKETSnap provides the metrics, intrinsic value calculator, and SWOT context so you can form your own view rather than rely on a single buy/sell rating.

ARWR

1-day price chart preview. Log in for 1W through 5Y ranges and period tabs.

Daily snapshot

-3.51
MARKETSnap

Trading Metrics:

Open: 73.33   Previous Close: 73.33
Day Low: 69.51   Day High: 74.87
Year Low: 14.3   Year High: 82.26
Price Avg 50: 71.73   Price Avg 200: 55.95
Volume: 78565   Average Volume: 2.025M

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See in Nexus

Relevant news

Arrowhead Pharmaceuticals Lines Up SHASTA Readout as REDEMPLO Launch Gains Traction
05-06-2026 14:04
Arrowhead Pharmaceuticals Lines Up SHASTA Readout as REDEMPLO Launch Gains Traction
Arrowhead Pharmaceuticals Presents New Positive Clinical Cardiometabolic Data at the 94th European Atherosclerosis Society (EAS) Congress
26-05-2026 10:00
Arrowhead Pharmaceuticals Presents New Positive Clinical Cardiometabolic Data at the 94th European Atherosclerosis Society (EAS) Congress
Arrowhead Pharmaceuticals Eyes Q3 SHASTA Data as REDEMPLO Approvals Build Momentum
20-05-2026 10:08
Arrowhead Pharmaceuticals Eyes Q3 SHASTA Data as REDEMPLO Approvals Build Momentum
Arrowhead Pharmaceuticals, Inc. (ARWR) Presents at Bank of America Global Healthcare Conference 2026 Transcript
14-05-2026 21:50
Arrowhead Pharmaceuticals, Inc. (ARWR) Presents at Bank of America Global Healthcare Conference 2026 Transcript
Arrowhead Pharmaceuticals Eyes $4B REDEMPLO Opportunity as RNAi Pipeline Readouts Near
14-05-2026 05:09
Arrowhead Pharmaceuticals Eyes $4B REDEMPLO Opportunity as RNAi Pipeline Readouts Near
Rhumbline Advisers Buys 11,115 Shares of Arrowhead Pharmaceuticals, Inc. $ARWR
20-02-2026 03:21
Rhumbline Advisers Buys 11,115 Shares of Arrowhead Pharmaceuticals, Inc. $ARWR

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